Searched over 200M research papers
10 papers analyzed
Some studies suggest pioglitazone alleviates gastrointestinal symptoms in animal models, while other studies do not provide evidence for such effects in humans.
20 papers analyzed
Pioglitazone, a thiazolidinedione class drug, is primarily used to improve insulin sensitivity in patients with type 2 diabetes. It has been studied for various effects beyond glycemic control, including its impact on liver function, cardiovascular risk markers, and gastrointestinal symptoms. This synthesis aims to determine whether pioglitazone improves gastrointestinal symptoms in humans.
Gastrointestinal Symptoms in IBS Models:
Gastroprotective Effects in Cirrhosis Models:
While there is evidence from animal models suggesting that pioglitazone can alleviate gastrointestinal symptoms such as those seen in IBS and provide gastroprotective effects in cirrhotic conditions, there is no direct evidence from human studies provided in the data. Further research in human subjects is needed to confirm these potential benefits.
Most relevant research papers on this topic
how to use ai within education?
is a crocodile a dinosaur
What is the role of artificial intelligence in enhancing the efficiency and accuracy of scientific research?
What are the challenges of developing gene therapies for genetic disorders?
deep rainforcement learning stock
How do I lower my risk of diabetes?