Drug utilisation study on hypertension patient
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Drug Utilization Study on Hypertension Patients
Introduction
Hypertension is a prevalent condition that significantly increases the risk of cardiovascular diseases. Effective management of hypertension often involves the use of antihypertensive medications. This study aims to analyze the utilization patterns of antihypertensive drugs among patients with hypertension, drawing on data from various research studies.
Key Findings
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Trends in Antihypertensive Medication Use
- A study examining trends in the United States found that the use of antihypertensive medications among adults increased from 57.3% in 1988-1994 to 62.9% in 1999-2002. The increase was more pronounced in men compared to women.
- Another study highlighted that multiple antihypertensive drug use increased from 29.1% to 35.8% over the same period, with significant increases in the use of calcium channel blockers, β-blockers, and ACE inhibitors.
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Utilization Patterns in Different Settings
- The Queen Mary Utilization of Antihypertensive Drugs Study (QUADS) reported that the use of multiple drugs for blood pressure control increased over time, with calcium channel blockers and β-blockers being consistently popular choices.
- In a tertiary care hospital in India, calcium channel blockers were the most commonly prescribed antihypertensive drugs, followed by β-blockers and angiotensin receptor blockers.
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Challenges in Hypertension Management
- A study conducted in a private healthcare setting in Nigeria found that while a combination of two drugs was frequently prescribed, there was a notable underuse of fixed-dose combination therapies, which are recommended to improve adherence.
- Another study focusing on hypertensive veterans with complex medication profiles found that while there was good adherence to recommended guidelines, there was still room for improvement in the utilization of β-blockers and diuretics.
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Impact of Comorbidities
- Among patients with hypertension and diabetes, ACE inhibitors were the most frequently used medications, reflecting adherence to clinical guidelines.
- For patients with hypertension and congestive heart failure, diuretics and ACE inhibitors were the most commonly used drugs, again indicating adherence to recommended treatment protocols.
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Global Perspectives
- A study in Italy highlighted suboptimal drug utilization and clinical outcomes in hypertensive patients, with a significant proportion of patients not achieving target blood pressure levels.
- In China, the use of antihypertensive drugs was found to be in line with national and European guidelines, with a high prevalence of combination therapy.
Conclusion
The utilization of antihypertensive medications varies across different regions and healthcare settings. While there have been improvements in the use of multiple drug therapies and adherence to clinical guidelines, challenges remain in achieving optimal blood pressure control. Further efforts are needed to enhance prescribing practices, particularly in the use of fixed-dose combination therapies and the management of patients with comorbid conditions.
References
- Antihypertensive Medication Use Among US Adults With Hypertension.
- Queen Mary Utilization of Antihypertensive Drugs Study: use of antihypertensive drug classes in the hypertension clinic 1996-2004.
- Drug Utilization Patterns of Anti Hypertensive Medication in a Tertiary Care Hospital.
- Antihypertensive Medication Use Among US Adults With Hypertension.
- Treatment of Hypertension in Primary Care.
- Antihypertensive Drug Utilization in Hypertensive Veterans With Complex Medication Profiles.
- Antihypertensive agent utilization patterns among patients with uncontrolled hypertension in the United States.
- Drug Utilization Pattern of Antihypertensives in a Private Healthcare Setting in Enugu, Nigeria.
- Analysis of Utilization of Antihypertensive Drugs.
- Study on drug utilization pattern of antihypertensive medications on out-patients and inpatients in a tertiary care teaching hospital: A cross sectional Study.
Sources and full results
Most relevant research papers on this topic
1
1
Antihypertensive Medication Use Among US Adults With Hypertension
2006·145Citations·Q. Gu et al.·
Circulation
2
2
Queen Mary Utilization of Antihypertensive Drugs Study: use of antihypertensive drug classes in the hypertension clinic 1996-2004.
2005·17Citations·B. Cheung et al.·
British journal of clinical pharmacology
3
3
DRUG UTILIZATION PATTERNS OF ANTI HYPERTENSIVE MEDICATION IN A TERTIARY CARE HOSPITAL
2015·1Citations·R. Pathapati et al.·
Journal of Evolution of medical and Dental Sciences
4
4
Antihypertensive Medication Use Among US Adults With Hypertension
2006·21Citations·QiupingGu et al.·
Circulation
5
5
TREATMENT OF HYPERTENSION IN PRIMARY CARE
2019·0Citations·G. Rigon et al.·
Journal of Hypertension
6
6
Antihypertensive Drug Utilization in Hypertensive Veterans With Complex Medication Profiles.
2000·30Citations·B. Carter et al.·
Journal of clinical hypertension
7
7
Antihypertensive agent utilization patterns among patients with uncontrolled hypertension in the United States
2020·4Citations·C. LaVallee et al.·
The Journal of Clinical Hypertension
8
8
Drug Utilization Pattern of Antihypertensives in a Private Healthcare Setting in Enugu, Nigeria
2022·0Citations·N. Udem·
TEXILA INTERNATIONAL JOURNAL OF PUBLIC HEALTH
9
9
Analysis of Utilization of Antihypertensive Drugs
2008·0Citations·Dai Yong·
Evaluation and Analysis of Drug-Use in Hospitals of China
10
10
Study on drug utilization pattern of antihypertensive medications on out-patients and inpatients in a tertiary care teaching hospital: A cross sectional Study
2015·16Citations·Nachiya R A M Jainaf et al.·
African Journal of Pharmacy and Pharmacology