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These studies suggest that fluoride toothpastes effectively prevent dental caries, with higher concentrations and supervised use increasing effectiveness, but may increase the risk of fluorosis in developing teeth.
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Fluoride toothpaste is a cornerstone in dental care, primarily used to prevent dental caries (tooth decay) and maintain oral hygiene. The addition of fluoride to toothpaste has been shown to significantly reduce the incidence of caries in both children and adults. This article synthesizes recent research on the benefits and effectiveness of fluoride toothpastes, particularly those with higher fluoride concentrations.
Research consistently shows that fluoride toothpaste is effective in preventing dental caries in children and adolescents. Studies indicate that the caries-preventive effect increases with higher fluoride concentrations. For instance, toothpastes with fluoride concentrations of 1000 ppm and above significantly reduce caries compared to non-fluoride toothpastes . A meta-analysis revealed that toothpastes with 2400-2800 ppm fluoride provide a 36% reduction in caries compared to a 23% reduction with 1000-1250 ppm fluoride.
High-fluoride toothpastes, particularly those containing stannous fluoride (SnF), have been shown to reduce erosive enamel wear. In a study where volunteers used SnF-containing toothpastes, the average erosive wear depth was significantly reduced by 34% and 26% with two different SnF formulations, compared to a non-significant 7% reduction with sodium fluoride toothpaste. This suggests that SnF toothpastes are particularly effective in protecting against dental erosion.
Fluoride toothpastes that include additional antimicrobial agents, such as o-cymen-5-ol and zinc chloride, offer enhanced benefits. These ingredients help in reducing plaque, gingival index, and bleeding, while also providing long-lasting breath freshness by reducing volatile sulfur compounds (VSCs). Importantly, these added benefits do not compromise the primary caries-preventive effects of fluoride.
For preschool children, standard fluoride toothpastes (1000-1500 ppm) are effective in reducing dental caries. A systematic review and meta-analysis found significant caries reduction at the surface, tooth, and individual levels when using standard fluoride toothpastes compared to placebo or no intervention. Low fluoride toothpastes (<600 ppm) were only effective at the surface level, indicating that higher fluoride concentrations are more beneficial for this age group.
In adults, fluoride toothpastes with concentrations of 1000-1100 ppm have been shown to reduce caries increment in the permanent dentition. The evidence suggests that these concentrations are effective in preventing caries across all age groups.
While the benefits of fluoride toothpaste are well-documented, there are concerns about the risk of dental fluorosis, particularly in young children. The evidence suggests that starting the use of fluoride toothpaste in children under 12 months may increase the risk of fluorosis. Therefore, the choice of fluoride concentration should balance the risk of caries with the potential for mild fluorosis.
High-fluoride toothpastes are highly effective in preventing dental caries and reducing erosive wear. They offer additional benefits for gingival health and plaque control without compromising their primary function. However, the choice of fluoride concentration should be carefully considered, especially for young children, to balance the benefits against the risk of fluorosis. Overall, the use of fluoride toothpaste remains a critical component of effective oral health care.
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