Facial creases treatment
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Effective Treatments for Facial Creases
Facial creases, commonly known as wrinkles, are a natural part of the aging process but can also be exacerbated by factors such as sun exposure, genetic disposition, and habitual muscle movements. Various treatments have been developed to address these creases, ranging from surgical interventions to injectable fillers and novel technologies. This article synthesizes the latest research on the most effective treatments for facial creases.
Mimetic Modulation for Facial Creases
Mimetic modulation involves the regulation of hyperactive facial muscles through procedures such as selective myotomy, myectomy, and neurotomy. These techniques target specific muscles responsible for creases, such as the frontalis, corrugators, and orbicularis oculi. Clinical studies have shown that mimetic modulation can be performed alone or in combination with other aesthetic procedures like blepharoplasty and rhytidectomy, providing significant improvements in facial aesthetics. However, potential complications include paresthesia, hypesthesia, partial paresis, and asymmetry1.
Hyaluronic Acid Fillers for Nasolabial Folds
Hyaluronic acid (HA) fillers are widely used to treat moderate-to-severe nasolabial folds. A study comparing HA gel with lidocaine (HARDL) and without lidocaine (HAJUP) found both formulations to be effective in reducing wrinkle severity, with improvements sustained up to 48 weeks post-treatment. The safety profiles of both treatments were comparable, with adverse events reported in 43% of subjects, though only 12% were treatment-related2.
Zyplast and Zyderm Collagen Implants
Zyplast and Zyderm collagen implants are used to correct age- and disease-related facial contour deficiencies. Zyplast, a gluteraldehyde crosslinked collagen, has shown superior results in some aspects compared to Zyderm II collagen. However, the effects diminish after six months, necessitating repeated injections every four to six months to maintain cosmetic correction3 7.
High-Intensity Facial Electromagnetic Stimulation (HIFES)
High-intensity facial electromagnetic stimulation (HIFES) combined with synchronized radiofrequency (RF) has shown promising results in increasing muscle mass density and the number of myonuclei and muscle fibers. This novel technology enhances muscle tissue structure, which may help maintain facial appearance and reduce creases. No adverse events were observed in the treated animals, indicating a favorable safety profile4.
String Fat/Dermis Grafts
String fat/dermis grafts offer a minimally invasive technique to address stubborn facial rhytides and minor depressed scars. This method involves harvesting fat or dermis, forming it into strings, and implanting it into subcutaneous tunnels beneath the creases. Clinical results have shown this technique to be simple, reliable, and effective for treating limited rhytides or depressed scars5 8.
Botulinum Toxin A for Upper Face Creases
Botulinum toxin A injections are a well-established treatment for upper face creases, including transverse striations, glabella lines, and crow's feet. Studies have demonstrated a 100% effectiveness rate in reducing dynamic creases, with minimal adverse reactions, making it a safe and straightforward option for facial rejuvenation6.
Dermal and Facial Autografts
Dermal and facial autografts are used in conjunction with facial aesthetic surgery to correct crease lines in areas such as the glabella and nasolabial folds. This technique has shown better long-term results compared to collagen or fat injections, with well-maintained graft volume and few complications9.
Injectable Microimplants
Injectable microimplants, such as biphasic copolymer (Bioplastique™), have been used to improve facial contours and fill deep creases. Preliminary reports indicate that these microimplants can effectively enhance facial aesthetics, although further studies are needed to fully establish their efficacy and safety10.
Conclusion
The treatment of facial creases involves a variety of methods, each with its own advantages and potential drawbacks. Mimetic modulation, hyaluronic acid fillers, collagen implants, HIFES, string fat/dermis grafts, botulinum toxin A, dermal autografts, and injectable microimplants all offer effective solutions for reducing facial wrinkles. The choice of treatment should be tailored to the individual patient's needs, considering factors such as the severity of creases, desired outcomes, and potential side effects.
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Most relevant research papers on this topic
Mimetic modulation for problem creases of the face
Mimetic modulation effectively treats problem creases in the face, improving the results of facial aesthetic surgery.
Comparison of Hyaluronic Acid Gel With (HARDL) and Without Lidocaine (HAJUP) in the Treatment of Moderate-To-Severe Nasolabial Folds: A Randomized, Evaluator-Blinded Study
Both HARDL and HAJUP effectively and safely improve moderate-to-severe nasolabial folds, with no significant difference in effectiveness or safety between the two treatments.
RCTClinical use of Zyplast in correction of age- and disease-related contour deficiencies of the face
Zyplast collagen is effective for treating age-related facial contour deficiencies, but requires repeated "top-up" injections for satisfactory results.
Observational StudyNovel Technology for Facial Muscle Stimulation Combined With Synchronized Radiofrequency Induces Structural Changes in Muscle Tissue: Porcine Histology Study
The HIFES + RF procedure effectively increases muscle mass density, myonuclei, and fibers in facial muscles, potentially benefiting facial appearance maintenance in human patients.
RCT
Animal StudyString Fat/Dermis Graft for Correction of Wrinkles and Scars.
String fat grafting is a simple and reliable method for addressing limited facial rhytides and minor depressed scars without needing another incision.
Observational StudyThe Treatment For Upper Half-Face Creases Withthe Botulinum Toxin A
Botulinum toxin A is a simple, safe, and effective treatment for upper half-face creases, with 100% effective power and one allergic response.
Observational StudyCorrection of age- and disease-related contour deficiencies of the face
Zyderm® Collagen Implants can effectively correct acne scars and facial wrinkles, but require careful assessment and informed consent before treatment.
String Fat/Dermis Graft for Correction of Wrinkles and Scars.
String fat graft is a simple and reliable method for addressing limited facial rhytids and minor depressed scars without needing another incision.
Observational StudyDermal and facial autografts in facial aesthetic surgery
Dermis grafts in facial aesthetic surgery provide better long-term results than collagen or fat injections, with minimal complications.
Utilization of injectable microimplants in aesthetic facial surgery
Injectable microimplants (BioplastiqueTM) can improve facial contours and fill deep creases and folds in aesthetic facial surgery, with potential for future use in cosmetic facial surgery.
Case Report