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These studies suggest that high intake of red and processed meat, alcohol, and fat-rich foods increases cancer risk, while a diet rich in whole grains, fruits, vegetables, dairy products, and plant-based foods may reduce it.
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High consumption of red and processed meats has been consistently linked to an increased risk of colorectal cancer. Studies show that for every 100 grams per day increase in red meat intake, the risk of colorectal cancer increases by 12% . Similarly, processed meats, such as sausages and bacon, are associated with a 17% increase in risk for every 50 grams consumed daily. These meats contain carcinogenic compounds formed during processing and cooking, such as heterocyclic amines (HCAs) and polycyclic aromatic hydrocarbons (PAHs), which can damage DNA and promote cancer development.
Alcohol consumption is another significant risk factor for various cancers, including those of the oral cavity, pharynx, esophagus, liver, and breast. Each 10 grams per day increase in ethanol intake from alcoholic beverages raises the risk of colorectal cancer by 7%. Alcohol can act as a solvent, enhancing the penetration of other carcinogens into cells, and its metabolism produces acetaldehyde, a toxic compound that can damage DNA.
Diets high in calories and fat are linked to obesity, which is a known risk factor for several cancers, including those of the esophagus, colorectum, breast (postmenopausal), endometrium, and kidney. Obesity can lead to chronic inflammation, insulin resistance, and hormonal imbalances, all of which can contribute to cancer development.
Salt-preserved foods, such as pickled vegetables and salted fish, have been associated with an increased risk of stomach cancer. The high salt content can damage the stomach lining and increase the risk of infection with Helicobacter pylori, a bacterium linked to stomach cancer.
Consumption of sugar-sweetened beverages and foods high in refined sugars can contribute to obesity and insulin resistance, both of which are risk factors for cancer. These foods can also promote inflammation and oxidative stress, further increasing cancer risk .
Consuming very hot foods and drinks can increase the risk of cancers of the oral cavity, pharynx, and esophagus. The high temperatures can cause thermal injury to the mucosal lining, leading to chronic inflammation and an increased risk of cancer.
Certain food contaminants, such as aflatoxins found in improperly stored grains and nuts, are potent carcinogens linked to liver cancer. Additionally, HCAs formed during the high-temperature cooking of meat can increase the risk of cancers such as those of the breast, colon, and prostate .
The evidence strongly suggests that certain foods and dietary patterns can significantly increase the risk of various cancers. High intake of red and processed meats, alcohol, high-calorie and fat-rich foods, salt-preserved foods, sugar-sweetened beverages, and very hot foods and drinks are all associated with increased cancer risk. Reducing the consumption of these foods and adopting a diet rich in whole grains, fruits, vegetables, and low-fat dairy products can help lower the risk of cancer.
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