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These studies suggest that a fasting plasma glucose level of 104 mg/dL is within a range that may indicate a significant risk of developing diabetes, particularly in certain populations.
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Fasting plasma glucose (FPG) levels are a critical measure for assessing metabolic health. In a study involving 4,170 non-diabetic adults, the median FPG levels were found to be slightly higher in men (103-107 mg/dL) compared to women (96-104 mg/dL). This suggests that a fasting glucose level of 104 mg/dL falls within the upper range of normal for women and is typical for men. The study also noted that FPG levels are relatively stable across different ages and body mass indices, indicating that a glucose level of 104 mg/dL is generally considered normal for most adults.
For pregnant women, glucose tolerance tests are used to diagnose gestational diabetes mellitus (GDM). A study comparing 75 gm and 100 gm glucose loads found that in metabolically healthy pregnant women, 2-hour glucose levels after a 75 gm load were around 104 mg/dL. This indicates that a glucose level of 104 mg/dL post-load is within the expected range for non-diabetic pregnant women. However, for those with GDM, glucose levels tend to be higher, and the 2-hour levels after a 75 gm load were significantly elevated.
A glucose level of 104 mg/dL is particularly significant when considering the risk of future diabetes. Research from the Omiya MA cohort study showed that individuals with FPG levels between 100-104 mg/dL had a significantly higher risk of developing diabetes compared to those with FPG levels below 85 mg/dL. Specifically, the hazard ratio for developing diabetes was 3.83 for those with FPG levels in the 100-104 mg/dL range, highlighting the importance of monitoring and potentially managing glucose levels even within this seemingly normal range.
In patients with acute pancreatitis (AP), blood glucose levels can influence the length of hospital stay (LOS). A study analyzing data from the MIMIC-III database found that patients with glucose levels greater than 104 mg/dL had a significantly higher risk of prolonged hospital stays compared to those with glucose levels between 68-104 mg/dL. This underscores the importance of maintaining glucose levels within a controlled range to potentially reduce hospital stay durations and improve recovery outcomes in AP patients.
A glucose level of 104 mg/dL is generally within the normal range for fasting plasma glucose, particularly for men and non-diabetic women. However, it is on the higher end of the spectrum and warrants attention due to its association with an increased risk of developing diabetes and implications for hospital stays in acute conditions like pancreatitis. Regular monitoring and appropriate lifestyle or medical interventions may be necessary to maintain optimal glucose levels and prevent future health complications.
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