Headache and nausea and tired
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Understanding Headache, Nausea, and Fatigue: Causes and Connections
Migraine-Related Symptoms: Headache, Nausea, and Fatigue
Migraines are a common cause of headaches accompanied by nausea and fatigue. These symptoms are often interlinked, with nausea being a defining feature of migraines. Studies have shown that migraines typically present with unilateral throbbing headaches, nausea, and significant fatigue, which can severely impact daily life1 7. The American Migraine Prevalence and Prevention (AMPP) study highlights the substantial burden of migraine-associated nausea, emphasizing its frequency and impact on individuals with migraines1.
Hangover Symptoms: Headache, Nausea, and Fatigue
Hangovers are another common scenario where headache, nausea, and fatigue co-occur. A nationwide randomized trial evaluated the efficacy of loxoprofen sodium in alleviating these symptoms post-hangover. The study found that while loxoprofen was effective in reducing headache severity, it did not significantly alleviate nausea or general fatigue2. This suggests that while some treatments may target specific symptoms, comprehensive relief from all hangover-related symptoms remains challenging.
Chronic Conditions: Fatigue, Headache, and Nausea
Chronic conditions such as chronic fatigue syndrome/myalgic encephalomyelitis (CFS/ME) and postural orthostatic tachycardia syndrome (POTS) often present with a combination of fatigue, headache, and nausea. Adolescents with CFS/ME frequently experience these symptoms, which can severely disrupt their daily activities and school attendance. Behavioral treatments, including cognitive-behavioral therapy, have shown promise in managing these symptoms and improving quality of life8 9.
Neurological and Medical Conditions
Certain neurological conditions can also present with headache, nausea, and fatigue. For instance, a case study of a woman with a sellar neoplasm (a type of brain tumor) reported these symptoms, which persisted even after surgical intervention3. Similarly, patients with impacted teeth have been found to experience a range of symptoms, including headache, nausea, and fatigue, which improve upon removal of the impactions5.
Environmental and External Factors
Environmental factors can also contribute to these symptoms. For example, a patient undergoing home dialysis experienced a syndrome of headache, chills, sweating, nausea, and exhaustion due to copper contamination in the dialysis system. Removing the copper parts resolved the symptoms, highlighting the impact of external factors on health6.
Conclusion
Headache, nausea, and fatigue are interconnected symptoms that can arise from various conditions, including migraines, hangovers, chronic illnesses, neurological issues, and environmental factors. Understanding the underlying cause is crucial for effective management and treatment. While some treatments may alleviate specific symptoms, a comprehensive approach is often necessary to address the full spectrum of these debilitating symptoms.
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Most relevant research papers on this topic
Frequency and Burden of Headache‐Related Nausea: Results From the American Migraine Prevalence and Prevention (AMPP) Study
While nausea is a defining feature of migraine, the association of nausea with other headache features and its influence on the burden of migraine have not been quantified. Population‐based data were used to elucidate the relative frequency and burden of migraine‐associated nausea in persons with migraine.
Observational Study
Highly CitedA Nationwide Randomised, Double-Blind, Placebo-Controlled Physicians' Trial of Loxoprofen for the Treatment of Fatigue, Headache, and Nausea after Hangovers.
Loxoprofen sodium effectively relieves headaches after hangovers but does not significantly affect general fatigue or nausea.
RCTTTF-1 Expressing Sellar Neoplasm with Ependymal Rosettes and Oncocytic Change: Mixed Ependymal and Oncocytic Variant Pituicytoma
A 1.7-cm sellar mass with suprasellar extension and contact with the optic apparatus was diagnosed in a 41-year-old woman with nausea, headaches, and fatigue.
Case ReportHeadache · fatigue · blurred vision · Dx?
One month after moving into her mother's apartment, a 27-year-old woman sought care at our clinic for fatigue, headache, blurred vision, nausea, and morning vomiting. She had weakness and difficulty sleeping, but denied any fever, rashes, neck stiffness, recent travel, trauma, or tobacco or illicit drug use. She did, however, have a 6-year history of migraines.
Case Report"Fatigue on rest" and associated symptoms (headache, vertigo, blurred vision, nausea, tension and irritability) due to locally asymptomatic, unerupted, impacted teeth.
Locally asymptomatic, unerupted impacted teeth can cause fatigue, headaches, vertigo, and other symptoms, with removal of the impactions alleviating these symptoms.
Haemodialysis and copper fever.
Copper-containing parts in home dialysis systems can cause headaches, chills, sweating, nausea, and exhaustion, but removing these parts can cure the syndrome.
Case ReportAn Update: Pathophysiology of Migraine.
Migraine likely results from dysfunctional homeostatic mechanisms, with abnormal central nervous system responses to extrinsic and intrinsic cues increasing attack susceptibility.
Highly CitedIs there effective behavioural treatment for children with chronic fatigue syndrome/myalgic encephalomyelitis?
Behavioral treatments may improve school attendance and fatigue in adolescents with chronic fatigue syndrome/myalgic encephalomyelitis.
Systematic Review
Very Rigorous JournalAdolescent fatigue, POTS, and recovery: a guide for clinicians.
Adolescent fatigue and POTS can be managed with multi-faceted treatment plans, including increased fluid and salt intake, aerobic exercise, regular sleep schedules, medications, and psychological support.
Highly CitedCaffeine in the management of patients with headache
Caffeine combined with analgesic medications significantly improves efficacy in treating tension-type headache and migraine, with favorable tolerability in most patients.
Systematic Review
Rigorous JournalHighly Cited