Searched over 200M research papers for "headache areas"
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These studies suggest that headache areas can vary widely, including the cranio-cervical region, head and neck muscles, occipital region, and front-orbital areas, with different mechanisms and triggers such as stress, physical trauma, and environmental changes.
20 papers analyzed
Research has shown that patients with migraines, tension-type headaches (TTH), and cervicogenic headaches (CeH) exhibit decreased pressure pain thresholds (PPT) in the cranio-cervical region. This decrease is indicative of sensitization in the trigemino-cervical nucleus caudalis. The trapezius muscle, particularly the midpoint between vertebrae C7 and the acromion, is frequently targeted and shows significantly lower PPT values in adults with migraines and chronic TTH compared to controls. This suggests that the cranio-cervical region is a critical area for understanding and diagnosing different types of headaches.
In chronic tension-type headaches (CTTH), active trigger points (TrPs) in the head and neck muscles can reproduce the headache pain pattern. Studies comparing adults and children with CTTH found that adults tend to have a higher number of active TrPs and more intense and longer-lasting headaches. The referred pain areas from these TrPs are larger in children, particularly in the upper trapezius, sternocleidomastoid, and temporalis muscles. This indicates that the anatomical localization of pain can vary significantly between different age groups.
Modern neuroimaging techniques have revolutionized our understanding of headache pathophysiology. Functional imaging studies have identified specific brain regions involved in different headache syndromes. For instance, activation in the brainstem is associated with migraines, while the hypothalamic grey matter is linked to trigeminal-autonomic headaches. These findings suggest that primary headaches are predominantly driven by central mechanisms, necessitating treatments that target both central and peripheral pathways.
A population-based imaging study investigated the cerebral cortical dimensions in individuals aged 50-66 years with and without headaches. The study found no significant differences in cortical volume, thickness, or surface area between headache sufferers and non-sufferers in key brain regions such as the anterior cingulate cortex, prefrontal cortex, and insula. This suggests that structural changes in the cerebral cortex are minimal or non-existent in the general population of headache sufferers.
Cluster headaches are typically localized in the orbital, supraorbital, or temporal regions. However, there are cases where cluster headaches present with pain in the occipital region. This highlights the importance of considering cluster headaches in the differential diagnosis even when the pain occurs in atypical locations.
Nummular headache (NH) is characterized by localized, round areas of pain on the scalp. Although it is uncommon for NH to present with more than one area of pain, there are rare cases where patients experience multiple pain sites simultaneously. This condition is thought to be due to a neuropathy of a terminal branch of a cutaneous scalp nerve or a focal nociceptive-type pain from epicranial tissues.
The research highlights the complexity and variability of headache areas, emphasizing the need for precise diagnostic criteria and targeted treatments. From the cranio-cervical region's sensitivity in migraines and TTH to the unique pain patterns in cluster headaches and nummular headaches, understanding the specific areas affected by different headache types is crucial for effective management and therapy.
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