Hemp extract benefits
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Benefits of Hemp Extract: A Comprehensive Overview
Introduction to Hemp Extract Benefits
Hemp extract, derived from the Cannabis sativa plant, has garnered significant attention for its potential health benefits. This article synthesizes recent research findings on the various advantages of hemp extract, focusing on its impact on wellness, stress resilience, antioxidant properties, anti-inflammatory effects, and more.
Wellness and Stress Resilience
Improved HDL Cholesterol and Sleep Quality
A study involving overweight but otherwise healthy individuals found that daily supplementation with hemp oil extract significantly improved HDL cholesterol levels and sleep quality. Participants reported better sleep quantity and a tendency towards enhanced stress resilience and life pleasure 1. These findings suggest that hemp extract can support cardiovascular health and overall well-being.
Modulation of Stress and Inflammation
Research on rats demonstrated that oral ingestion of CBD-rich hemp extract reduced stress-induced inflammatory responses. The study highlighted sex-dependent differences, with females showing a more constrained inflammatory response compared to males. This suggests that hemp extract can modulate stress and inflammation, potentially offering benefits for both mental and physical health 3.
Antioxidant Properties
Enhanced Antioxidant Enzyme Activity
In honey bees, hemp extract significantly increased the activity of key antioxidant enzymes, such as catalase and superoxide dismutase. This enhancement in antioxidant activity helped protect the bees against free radicals and delayed aging processes, indicating the potent antioxidant properties of hemp extract 2.
Protection Against Oxidative Stress
In human fibroblasts and keratinocytes, hemp extract protected cells from oxidative stress-induced cytotoxicity and apoptosis. The extract also modulated IL-6 levels, a key mediator in skin proliferation, further supporting its antioxidant and protective effects on the skin 4.
Anti-Inflammatory Effects
Reduction of Inflammatory Markers
Hemp extract has shown promising anti-inflammatory properties. In isolated mouse skin specimens, the extract reduced hydrogen peroxide-induced prostaglandin-E2 production and other inflammatory markers. This suggests that hemp extract can effectively mitigate inflammation and protect against oxidative damage 4.
Synergistic Effects with Other Compounds
Combining hemp extract with other anti-inflammatory agents, such as palmitoylethanolamide (PEA), has been found to produce greater-than-additive effects in alleviating pain-related behaviors in mouse models. This combination also attenuated the transcription of inflammatory cytokines, indicating a synergistic anti-inflammatory effect 9.
Nutritional and Antimicrobial Properties
Nutritional Value
Hemp seeds and hempseed oil are rich in essential amino acids, fatty acids, vitamins, and minerals. These nutritional components contribute to the overall health benefits of hemp, making it a valuable addition to the diet 8.
Antimicrobial Properties
Hemp extract has demonstrated antimicrobial activity against various pathogens, including Staphylococcus aureus and Escherichia coli. This antimicrobial property, combined with its nutritional value, underscores the potential of hemp extract as a functional food ingredient 7.
Conclusion
The research reviewed highlights the multifaceted benefits of hemp extract, including its positive effects on cholesterol levels, sleep quality, stress resilience, antioxidant activity, anti-inflammatory properties, and nutritional value. These findings support the growing interest in hemp extract as a natural supplement for enhancing overall health and well-being.
Sources and full results
Most relevant research papers on this topic
Effects of Hemp Extract on Markers of Wellness, Stress Resilience, Recovery and Clinical Biomarkers of Safety in Overweight, But Otherwise Healthy Subjects
Hemp supplementation improved HDL cholesterol, tended to support psychometric measures of perceived sleep, stress response, and perceived life pleasure, and was well tolerated with no clinically relevant safety concerns.
RCTImpressive Impact of Hemp Extract on Antioxidant System in Honey Bee (Apis mellifera) Organism
Hemp extract significantly increases the antioxidant system in honey bees, extending their lifespan and protecting them from free radicals.
RCT
Animal Study
Rigorous JournalOral CBD-rich hemp extract modulates sterile inflammation in female and male rats
Oral CBD-rich hemp extract reduces stress-induced inflammation in female rats, with potential sex and tissue-dependent effects.
RCTAnimal StudyMetabolomic Profile and Antioxidant/Anti-Inflammatory Effects of Industrial Hemp Water Extract in Fibroblasts, Keratinocytes and Isolated Mouse Skin Specimens
Hemp water extract, containing cannabidiol, cannabidiolic acid, and rutin, effectively protects skin from oxidative stress and inflammation, with potential benefits for topical use.
In Vitro StudyRigorous JournalHemp (Cannabis Sativa L.) Extract: Anti-Microbial Properties, Methods of Extraction, and Potential Oral Delivery
Hemp extracts have potential health benefits, including anti-microbial properties and nutritional value, and new extraction methods using nano-carriers show promise for oral delivery of cannabinoids.
Highly CitedHemp in Veterinary Medicine: From Feed to Drug
Hemp and its derivatives show excellent nutritional and health-promoting properties in animal nutrition and therapeutics, with potential benefits for conditions like pain, inflammation, epilepsy, anxiety disorders, and nausea.
Natural Hemp-Ginger Extract and Its Biological and Therapeutic Efficacy
Hemp and ginger extract show a synergistic effect as a supportive treatment for skin diseases, with potential health benefits for prevention and treatment.
In Vitro StudyA Review of Hemp as Food and Nutritional Supplement.
Hemp, a valuable crop with numerous uses, offers health benefits and nutritional benefits when consumed as food or supplements, with CBD showing potent anxiolytic, spasmolytic, and anticonvulsant effects.
Literature ReviewHighly CitedPalmitoylethanolamide and hemp oil extract exert synergistic anti-nociceptive effects in mouse models of acute and chronic pain.
Hemp oil extract and palmitoylethanolamide (PEA) show synergistic anti-nociceptive effects, providing greater than additive relief for acute and chronic pain in mouse models.
Non-RCTAnimal StudyRigorous Journal