HIV chemotherapy has significantly reduced AIDS-related illness and death, but challenges remain, including drug-resistant virus and chronic therapy toxicity.

HIV chemotherapy : AIDS

"Treat All" policy implementation in sub-Saharan Africa requires focused research to promote timely treatment uptake, retention in care, and sustained viral suppression, while addressing bottlenecks impeding implementation.

Research priorities to inform “Treat All” policy implementation for people living with HIV in sub‐Saharan Africa: a consensus statement from the International epidemiology Databases to Evaluate AIDS (IeDEA)

AIDS prevention and treatment include antiviral therapy, but the incurability of the disease remains unsolved, with treatments only prolonging patients' lives.

Research on AIDS Prevention and Treatment

Stem cell transplantation from donors with a homozygous mutation in CCR532 may be a potential HIV cure, enabling remission of both HIV and a related haematological malignancy.

HIV cure: Are we going to make history?

HIV-infected patients in the ICU face high risks for critical illness, but advances in intensive care practices have improved short-term survival.

Management of HIV-infected patients in the intensive care unit

AIDS-related malignancies, despite highly active antiretroviral therapy, remain a leading cause of morbidity and mortality in HIV-infected patients.

AIDS-related malignancies: emerging challenges in the era of highly active antiretroviral therapy.

Protease inhibitors effectively treat HIV/AIDS, but face challenges in drug resistance, adverse effects, and challenges in their successful application in HAART regimens.

Protease Inhibitors for the Treatment of HIV/AIDS: Recent Advances and Future Challenges.

Gene therapy shows promising results in controlling HIV infection, offering a potential cure for millions of people worldwide.

Could gene therapy cure HIV?

HAART treatment has transformed HIV infection into a treatable chronic condition, allowing individuals to live normal and healthy lives when tested early and engaged in care.

Therapeutic Options for HIV Infection

Antiretroviral therapy has successfully transformed HIV into a potentially chronic disease, but strict lifelong drug adherence, potential long-term toxic effects, and high drug costs still limit treatment access.

Antiretroviral therapy and management of HIV infection

Stage- and risk-adapted treatment with combination antiretroviral therapy is effective for HIV-associated lymphoma patients, with high remission and survival rates similar to those achieved in HIV-negative patients.

Therapy of HIV-associated lymphoma—recommendations of the oncology working group of the German Study Group of Physicians in Private Practice Treating HIV-Infected Patients (DAGNÄ), in cooperation with the German AIDS Society (DAIG)

Effective treatment lowers viral load to undetectable levels, reducing HIV transmission, but current resources and challenges make a "test-and-treat" approach unrealistic.

HIV treatment for prevention

New treatments and anti-HIV drugs are continuously developed to control and cure AIDS, with the latest development being a novel bone marrow transplantation from donors with a homozygous mutation in CCR5 gene.

HIV: Biology to Treatment

Effective treatment with antiretroviral drugs can significantly reduce HIV transmission and help combat stigma, potentially improving social and sexual relationships among affected groups.

HIV Treatment as Prevention: Implications for Health Promotion

Early treatment of HIV-infected infants with antiretroviral therapy (ART) before 12 weeks of age reduces mortality by 75%, according to a study presented at the International AIDS Society meeting in Sydney, Australia.

Treating HIV-infected infants early prolongs life.

Antiretroviral treatment for HIV infection reduces classic AIDS-related conditions, but patients are at increased risk for non-AIDS complications like cardiovascular disease, malignancy, renal disease, and thrombosis.

HIV infection, antiretroviral treatment, ageing, and non-AIDS related morbidity

Renal transplantation in HIV patients has shown good outcomes with effective clinical strategies, despite concerns about immunosuppressants, limited donor organ supply, and viral transmission to surgical and medical staff.

Renal transplantation in patients with HIV

New strategies to engage men in HIV prevention and care are needed to overcome challenges like gender norms, stigma, and homophobia, and advance the MenStar Coalition.

Engaging men in HIV treatment and prevention

A test and treat strategy, combining antiretroviral therapy and testing, could potentially reduce HIV incidence, access to care, and health disparities in the United States.

Can we treat our way out of HIV?

Perceived barriers to antiretroviral therapy for children living with HIV/AIDS in Tamale Metropolis include denial of diagnosis, stock-outs, busy schedules, ignorance, alternative herbal cures, stigma, discrimination, and transportation.

“Some believe those who say they can cure it” perceived barriers to antiretroviral therapy for children living with HIV/AIDS: Qualitative exploration of caregivers experiences in tamale metropolis

These studies suggest that HIV/AIDS is primarily treated with antiretroviral therapy (HAART), which has transformed it into a chronic condition, though challenges like drug resistance, toxicity, and high costs remain, and potential cures such as gene therapy and stem cell transplantation are being explored.