How does cbd oil make you feel
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How Does CBD Oil Make You Feel?
Cannabidiol (CBD) oil, derived from the Cannabis sativa plant, has gained popularity for its potential therapeutic effects, particularly in alleviating symptoms of anxiety, stress, and pain. This article synthesizes findings from multiple studies to provide a comprehensive understanding of how CBD oil can make you feel.
CBD Oil and Symptom Relief in Advanced Cancer
A study on patients with advanced cancer explored whether CBD oil could improve symptom distress. Participants received titrated doses of CBD oil or a placebo over 28 days. The study found no significant difference in symptom distress reduction between the CBD and placebo groups. However, most participants reported feeling better or much better by the end of the study, regardless of whether they received CBD or placebo1. This suggests that while CBD oil may not significantly reduce symptom distress in advanced cancer patients, it can contribute to an overall sense of well-being.
CBD Expectancy and Its Psychological Effects
Research has shown that the belief in CBD's effects can influence how individuals feel. In a randomized crossover study, participants who believed they were taking CBD oil (but were actually given CBD-free hempseed oil) reported increased sedation and changes in heart rate variability, indicating heightened stress regulation. Those with strong beliefs in CBD's anxiolytic properties experienced significantly reduced anxiety when they thought they had taken CBD2 3. This highlights the powerful role of expectancy in the perceived effects of CBD oil.
Anxiolytic Effects in Social Anxiety Disorder
A study involving teenagers with social anxiety disorder (SAD) found that daily administration of CBD oil significantly reduced anxiety symptoms over four weeks. Participants reported decreased anxiety on both the Fear of Negative Evaluation Questionnaire and the Liebowitz Social Anxiety Scale5. This suggests that CBD oil can have a tangible anxiolytic effect, particularly in individuals with social anxiety.
General Therapeutic Benefits and Considerations
CBD oil is often reported to provide relief for various conditions, especially pain, without the intoxicating effects associated with medical marijuana. It has been approved for treating severe epilepsy, further highlighting its therapeutic potential. However, the lack of regulation and potential for inaccurate labeling of CBD products necessitates caution when selecting CBD oil4.
Conclusion
CBD oil can make you feel better by potentially reducing anxiety and contributing to an overall sense of well-being. The effects can be influenced by both the pharmacological properties of CBD and the individual's expectations. While CBD oil shows promise in treating conditions like social anxiety disorder, its efficacy in other areas, such as symptom distress in advanced cancer, may not be as significant. As always, it is essential to choose high-quality, accurately labeled CBD products to ensure safety and effectiveness.
Sources and full results
Most relevant research papers on this topic
Phase IIb Randomized, Placebo-Controlled, Dose-Escalating, Double-Blind Study of Cannabidiol Oil for the Relief of Symptoms in Advanced Cancer (MedCan1-CBD)
CBD oil did not add value to the reduction in symptom distress provided by specialist palliative care alone in advanced cancer patients.
RCT
Rigorous JournalEvaluating cannabidiol (CBD) expectancy effects on acute stress and anxiety in healthy adults: a randomized crossover study
CBD expectancy alone impacts sedation and heart rate variability, but only those with strong beliefs that CBD has anxiolytic properties experience reduced anxiety.
RCT
Very Rigorous JournalThe power of placebo: Does cannabidiol (CBD) expectancy alone impact acute stress and anxiety?
CBD expectancy alone can impact subjective and physiological responses, with strong beliefs about its stress- and anxiety-reducing properties leading to lower anxiety.
RCTClinicians' Guide to Cannabidiol and Hemp Oils.
Cannabidiol (CBD) oils show promise for treating various conditions, particularly pain, but careful selection and regulation are crucial for safe and effective patient care.
Systematic Review
Highly CitedAnxiolytic Effects of Repeated Cannabidiol Treatment in Teenagers With Social Anxiety Disorders
Repeated cannabidiol treatment significantly decreased anxiety in Japanese teenagers with social anxiety disorder.
RCTHighly CitedThe Long-Term Effect of CBD Crystals and CBD Oil on Depressive-Associated Rat Behaviors
Long-term consumption of CBD crystals and oil may elicit depression-associated symptoms in normal rats without depression, highlighting the need for extreme caution in using CBD-containing products.
RCTCannabidiol Oil for Decreasing Addictive Use of Marijuana: A Case Report.
CBD oil can decrease addictive use of marijuana and provide anxiolytic and sleep benefits, while maintaining non-use in a patient with bipolar disorder.
Case ReportNeural basis of anxiolytic effects of cannabidiol (CBD) in generalized social anxiety disorder: a preliminary report
CBD reduces anxiety in patients with generalized social anxiety disorder, likely due to its effects on limbic and paralimbic brain areas.
RCTVery Rigorous JournalHighly CitedDiversity of molecular targets and signaling pathways for CBD
CBD has diverse effects on various conditions, with serotonin 5HT1A and TRPV1 channels being main targets, and its effects may be due to multiple molecular mechanisms of action.
Literature ReviewRigorous JournalHighly CitedCannabidiol (CBD) use in psychiatric disorders: A systematic.
CBD shows potential therapeutic effects for specific psychiatric conditions, but more large-scale randomized controlled trials are needed to confirm its safety and efficacy.
Systematic ReviewHighly Cited