Searched over 200M research papers
10 papers analyzed
These studies suggest that preventing cardiovascular disease involves a combination of lifestyle changes, resource-efficient strategies, and targeted medical interventions, while also considering individual and community factors.
20 papers analyzed
Cardiovascular disease (CVD) remains a leading cause of morbidity and mortality worldwide. Effective prevention strategies are essential to reduce the global burden of this disease. This article synthesizes current research on various approaches to prevent CVD, focusing on lifestyle modifications, medication adherence, and community-based interventions.
Adopting a healthy diet and engaging in regular physical activity are foundational strategies for preventing CVD. Behavioral counseling interventions have been shown to improve dietary intake and physical activity levels, leading to modest reductions in blood pressure, low-density lipoprotein (LDL) cholesterol, and adiposity-related indices. The US Preventive Services Task Force (USPSTF) recommends that clinicians individualize the decision to offer or refer adults without CVD risk factors to behavioral counseling interventions to promote these healthy behaviors.
Primordial prevention focuses on preventing the development of risk factors through healthy lifestyle behaviors. The Healthy Heart Score, a lifestyle-based CVD prediction model, includes factors such as age, smoking, body mass index, exercise, alcohol consumption, and diet. This model has demonstrated good discrimination and calibration in identifying individuals at elevated risk for CVD, particularly among those without baseline hypertension or hypercholesterolemia.
Adherence to prescribed medications for the primary prevention of CVD is crucial but often suboptimal. Mobile phone-based interventions, including short messaging service (SMS) and smartphone applications, have shown potential in improving medication adherence. Some trials reported modest benefits in reducing LDL cholesterol and blood pressure, although the evidence is of low certainty due to high risk of bias and inconsistency in outcome effects . These interventions are scalable and cost-effective, making them a promising approach to enhance medication adherence and reduce CVD morbidity and mortality .
A study conducted in rural China evaluated a package of pharmaceutical and lifestyle interventions for patients with hypertension and/or diabetes. The intervention included standardized medication prescriptions, lifestyle advice, and adherence support. Although the intervention did not significantly reduce severe CVD events over 36 months, it did result in small but significant reductions in systolic and diastolic blood pressure. This suggests that comprehensive interventions combining medication and lifestyle modifications can be beneficial, but longer follow-up periods and improved health system factors, such as universal coverage for essential medicines, are needed for more substantial impacts.
General practitioners (GPs) play a critical role in CVD prevention by empowering patients and considering individual factors. GPs emphasize the importance of prescribing medication, motivating behavioral changes, and providing holistic care. They also recognize the challenges of overmedicalization and economic burdens on patients. Community-based strategies involving other health professionals and decision aids tailored to patients' health and environment can support GPs in their preventive efforts.
In low- and middle-income countries, resource-efficient strategies are essential to bridge the evidence-practice gaps in CVD prevention. Effective measures include tobacco control, simplified screening and management algorithms, affordable treatment regimens, and task-sharing with nonphysician health workers. These strategies target modifiable factors such as hypertension and secondary prevention, leading to significant reductions in CVD mortality.
Preventing cardiovascular disease requires a multifaceted approach that includes lifestyle modifications, improved medication adherence, and community-based interventions. While behavioral counseling and mobile phone-based interventions show promise, comprehensive and resource-efficient strategies are necessary to address the global burden of CVD effectively. Tailoring interventions to individual and community needs, along with ongoing research and adaptation, will be key to successful CVD prevention.
Most relevant research papers on this topic