The endocrine system plays a crucial role in regulating life-long physiology, and understanding its variation across one's lifespan is crucial for understanding age-related disorders and promoting gerontological research.

Endocrine Function in Aging

The endocrine system plays a crucial role in regulating energy production, metabolism, growth, reproduction, and response to internal and external stimuli.

Principles of Endocrinology and Hormone Action

The endocrine system plays a crucial role in maintaining homeostasis, controlling energy storage and utilization, regulating growth and reproduction, and controlling the body's responses to external stimuli, particularly stress.

Endocrine Physiology

The endocrine system regulates metabolism, growth, development, electrolyte balance, and reproduction, with various metabolic disorders linked to over or underproduction of hormones.

Physiology of Endocrine System and Related Metabolic Disorders

Understanding vascular changes in endocrine glands may help manage endocrine disorders and comorbidities associated with aging.

Heterogeneity and Dynamics of Vasculature in the Endocrine System During Aging and Disease

The endocrine system plays a crucial role in maintaining body homeostasis, and environmental factors can disrupt its function through stimulation or inhibition of hormone production and secretion.

Pathology of the Endocrine System

Hypothalamic neurohormone-expressing cells play a crucial role in appetite and metabolism regulation, with distinct contributions from neurohormones and neurotransmitters.

Neuroendocrine control of appetite and metabolism

The mid-1990s endocrine disruption concerns led to a shift in toxicology testing paradigms and a greater focus on endocrine-mediated toxicity mechanisms.

Endocrine disruption: historical perspectives and its impact on the future of toxicology testing.

The endocrine system plays a key role in aging and longevity, with hormones like growth hormone, insulin, and insulin playing key roles in these processes.

Endocrinology of Aging and Longevity

Leptin, ghrelin, adiponectin, and resistin play crucial roles in regulating energy metabolism, influencing various organ systems and influencing nutritional status.

Endocrine regulation of energy metabolism: review of pathobiochemical and clinical chemical aspects of leptin, ghrelin, adiponectin, and resistin.

Human pancreatic islets are sparsely contacted by autonomic axons, suggesting sympathetic nerves may regulate hormone secretion by controlling local blood flow or acting on downstream islet regions.

Innervation patterns of autonomic axons in the human endocrine pancreas.

Infections alter glucose metabolism, promoting the body's ability to fight infection, but these interactions can derail in obesity, exacerbated by metabolic diseases like diabetes mellitus type 2.

‘Beauty and the beast’ in infection: How immune–endocrine interactions regulate systemic metabolism in the context of infection

The endocrine system plays a crucial role in regulating growth, puberty, metabolism, and bone health in children, with common endocrinopathies affecting their health.

Biological basis of child health 12: the endocrine system and common childhood endocrinopathies.

Gut peptides and gut microbiota play a crucial role in regulating metabolic homeostasis and disease, with potential endocrine impacts on host metabolic tissue function.

Endocrine regulation of metabolic homeostasis via the intestine and gut microbiome.

The endocrine system plays a key role in regulating aging and longevity in mammals, with potential relevance to human longevity based on evidence from other species.

Hormonal regulation of longevity in mammals

Gut hormone secretion plays a crucial role in maintaining energy balance and glucose homeostasis, with interactions involving various organs and influenced by nutrients and gut microbiome metabolites.

Mechanisms controlling hormone secretion in human gut and its relevance to metabolism

Glucocorticoids and oxytocin play crucial roles in human-dog coexistence, affecting social tolerance and promoting social coordination and familiarity between individuals.

Endocrine Regulations in Human–Dog Coexistence through Domestication

Genome sequence information from non-osteichthyan vertebrates, such as jawless and cartilaginous fishes, helps understand the diversification of vertebrate gene repertoires and the evolutionary timing of gene origins.

Evolution of Vertebrate Hormones and Their Receptors: Insights from Non-Osteichthyan Genomes.

Pharmaceutical products can act as endocrine disrupting chemicals (EDCs) and contribute to metabolic disorders like insulin resistance and obesity through their discharge into the environment and their off-target interaction with the endocrine system.

Role of Pharmaceuticals as EDCs in Metabolic Disorders

Chemicals like chlorpyrifos and DDT disrupt the human endocrine system, leading to various diseases and potentially fatal consequences.

Chemicals that Disrupt the Endocrine System and their Effects on Human Health

How does the human endocrine system regulate bodily functions?

These studies suggest the endocrine system regulates metabolism, growth, reproduction, homeostasis, and responses to stimuli, with significant roles in aging and energy balance.