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These studies suggest that NMN may increase longevity by elevating NAD+ levels, enhancing sirtuin activity, and promoting cellular homeostasis, but further clinical investigations are needed to confirm its effectiveness and safety.
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Nicotinamide mononucleotide (NMN) has garnered significant attention as a potential anti-aging compound. As a precursor to nicotinamide adenine dinucleotide (NAD+), NMN is believed to play a crucial role in cellular metabolism and longevity. This synthesis aims to evaluate the current research on whether NMN can increase longevity.
NAD+ Levels and Aging:
Therapeutic Effects:
Mechanisms of Action:
Safety and Efficacy:
Current research suggests that NMN has the potential to increase longevity by elevating NAD+ levels, thereby improving cellular health and mitigating age-related diseases. However, while preclinical studies are promising, more extensive clinical trials are necessary to fully understand its efficacy and safety in humans.
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