Is smoking cbd bad
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Is Smoking CBD Bad? An Analysis of Current Research
Effects of Smoking CBD on Driving Ability
Research has investigated the impact of smoking CBD-rich marijuana on driving ability. A study involving 33 participants assessed reaction time, behavior under stress, and concentration performance after smoking a joint containing CBD-rich marijuana or a placebo. The results showed no significant differences between the effects of smoking CBD-rich marijuana and the placebo on these parameters. Although THC concentrations in the blood were detected, no signs of impairment were found, suggesting that higher CBD concentrations might prevent the formation of impairment symptoms typically associated with THC1.
CBD and Cardiovascular Effects
Another study explored the effects of oral CBD on the subjective, reinforcing, and cardiovascular effects of smoked cannabis. Participants who received CBD did not show significant changes in heart rate or subjective effects compared to those who received a placebo. This indicates that CBD alone does not produce significant psychoactive or cardiovascular effects and does not alter the effects of smoked cannabis2.
CBD as a Smoking Cessation Aid
CBD has shown promise as a potential aid for smoking cessation. In a pilot study, smokers who used a CBD inhaler reduced their cigarette consumption by approximately 40% compared to those who used a placebo inhaler. This suggests that CBD could be a useful tool for reducing cigarette consumption and aiding in smoking cessation3. Additionally, CBD has been found to reduce the salience and pleasantness of cigarette cues, which could help smokers manage cravings and withdrawal symptoms5.
Abuse Liability of CBD
Research has also examined the abuse liability of CBD. A study involving frequent marijuana users found that CBD did not produce any signals of abuse liability. Participants did not report significant subjective effects such as feeling "high" when taking CBD, indicating that it is unlikely to be abused4.
Pharmacokinetic Interactions
CBD and tobacco smoking both induce certain liver enzymes, which can affect the metabolism of various drugs. This interaction suggests that individuals who smoke both tobacco and CBD may experience additive effects on enzyme induction, potentially impacting the pharmacokinetics of other medications they are taking6.
Cognitive Effects During Nicotine Abstinence
The effects of CBD on cognitive functions during nicotine abstinence have also been studied. One study found that a single dose of CBD did not improve memory or reduce impulsivity in cigarette-dependent smokers during acute nicotine withdrawal. In fact, CBD increased commission errors on a go/no-go task, indicating that it might not be effective in improving cognitive performance during nicotine abstinence7.
Conclusion
Current research suggests that smoking CBD is not associated with significant negative effects on driving ability, cardiovascular health, or abuse liability. Additionally, CBD shows potential as a smoking cessation aid by reducing cigarette consumption and the salience of cigarette cues. However, its effects on cognitive performance during nicotine abstinence are inconclusive. As with any substance, it is important to consider individual responses and consult healthcare professionals when using CBD, especially in combination with other medications.
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Most relevant research papers on this topic
Impact of smoking cannabidiol (CBD)-rich marijuana on driving ability
Smoking CBD-rich marijuana does not impair driving ability, but consumers should avoid driving for several hours after smoking, as legal THC concentration limits may be exceeded.
RCTOral Cannabidiol does not Alter the Subjective, Reinforcing or Cardiovascular Effects of Smoked Cannabis
Oral CBD does not reduce the reinforcing, physiological, or positive subjective effects of smoked cannabis.
RCT
Very Rigorous Journal
Highly CitedCannabidiol reduces cigarette consumption in tobacco smokers: preliminary findings.
Cannabidiol (CBD) inhalation significantly reduced cigarette consumption by 40% in tobacco smokers, suggesting it as a potential treatment for nicotine addiction.
RCTHighly CitedOral cannabidiol does not produce a signal for abuse liability in frequent marijuana smokers.
Oral cannabidiol does not show any signals of abuse liability at the doses tested in frequent marijuana smokers, potentially informing regulatory decisions regarding its Schedule I status on the CSA.
RCTHighly CitedCannabidiol reverses attentional bias to cigarette cues in a human experimental model of tobacco withdrawal
Cannabidiol reduces attentional bias and pleasantness of cigarette cues in dependent smokers after overnight abstinence without affecting craving or withdrawal.
RCTHighly CitedPharmacokinetic Drug Interactions with Tobacco, Cannabinoids and Smoking Cessation Products
Tobacco and marijuana smoking induce CYP1A2, and smoking cessation may require dose reduction of CYP1A drugs to prevent toxicity.
Rigorous JournalHighly CitedThe effects of cannabidiol on impulsivity and memory during abstinence in cigarette dependent smokers
A single 800 mg dose of CBD does not improve verbal or spatial working memory, or reduce impulsivity during tobacco abstinence in cigarette dependent smokers.
RCTRigorous JournalCarbonyl Compounds in Mainstream Smoke of Hemp Cigarettes
Hemp cigarettes contain significant concentrations of carbonyl compounds, which may need to be reduced to balance harms and benefits when used for therapeutic purposes.
Determination of cannabinoids in urine, oral fluid and hair samples after repeated intake of CBD-rich cannabis by smoking.
Repeated intake of CBD-rich cannabis can generate positive results in biological samples, with THC levels increasing over time, but hair samples can help distinguish between CBD-rich and THC-prevalent products.
Non-RCTCannabinoid concentrations in confiscated cannabis samples and in whole blood and urine after smoking CBD-rich cannabis as a “tobacco substitute”
CBD-rich cannabis products can be used as tobacco substitutes, but trace amounts of THC can produce blood levels above the Swiss legal limit for driving, making the consumer unable to drive legally.
Observational StudyRigorous Journal