Is weed a psychedelic
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Is Weed a Psychedelic?
Understanding Cannabis and Psychedelics
Cannabis, commonly known as weed, and classic psychedelics like psilocybin and LSD are both controlled substances. However, they are often perceived and categorized differently in both scientific literature and public opinion. Classic psychedelics are known for their ability to induce profound changes in perception, mood, and cognitive processes, often leading to mystical or spiritual experiences. These effects are primarily mediated through the neuronal 5-HT2A receptor4.
Cannabis and Psychedelic Effects
Despite the common perception, there is emerging evidence suggesting that cannabis, particularly high-THC strains, can elicit effects similar to those of classic psychedelics. Research indicates that cannabis can induce perceptual changes, aversiveness, and mystical experiences, which are hallmark features of psychedelic experiences1. However, these effects are not consistently observed in controlled studies, possibly due to variations in dosage, setting, and individual differences1.
Therapeutic Potential of Cannabis and Psychedelics
Both cannabis and psychedelics have shown promise in the treatment of various psychiatric disorders. The therapeutic potential of cannabis, especially in high doses, is being explored for its ability to generate psychedelic experiences that could be beneficial in therapeutic settings1. Similarly, psychedelics are being investigated for their potential to treat substance use disorders, including cannabis use disorder (CUD)2. The mechanisms by which psychedelics may help in treating CUD include altering perception and cognition, which could reduce the compulsive use of cannabis2.
Cannabis as a Quasi-Psychedelic
Cannabis is sometimes referred to as a quasi-psychedelic due to its ability to produce effects that overlap with those of classic psychedelics, albeit typically less intense. This categorization is supported by its inclusion in studies alongside other substances like MDMA, salvinorin A, and ayahuasca, which are known for their psychedelic properties3. The therapeutic uses of these substances are being increasingly recognized, although research is often hampered by regulatory restrictions3.
Public Interest and Perception
Public interest in both cannabis and psychedelics has been growing, particularly during the COVID-19 pandemic. Online search trends indicate a significant increase in interest in these substances, reflecting a broader societal shift towards exploring their potential benefits and uses4. This growing interest underscores the need for more research to fully understand the effects and therapeutic potential of cannabis as a psychedelic.
Conclusion
While cannabis is not traditionally classified as a psychedelic, high-THC strains have the potential to produce psychedelic-like effects. These effects, combined with the therapeutic potential of cannabis, warrant further investigation. Understanding cannabis in the context of psychedelics could open new avenues for treatment and provide deeper insights into the mechanisms underlying altered states of consciousness.
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Most relevant research papers on this topic
The psychedelic effects of cannabis: A review of the literature
High-THC cannabis may elicit psychedelic effects, but current research may not accurately capture these effects due to dose, set, and settings.
Literature ReviewSystematic review and rationale of using psychedelics in the treatment of cannabis use disorder
Psychedelics show potential as a treatment for cannabis use disorder, with limited data and reporting, and more research is needed to understand their therapeutic potential and potential risks.
Systematic Review[Psychedelics and quasi-psychedelics in the light of contemporary research: medical cannabis, MDMA, salvinorin A, ibogaine and ayahuasca].
Psychedelic-like agents, such as medical cannabis, MDMA, salvinorin A, ibogaine, and ayahuasca, show promising therapeutic potentials under proper conditions.
Spatiotemporal Mapping of Online Interest in Cannabis and Popular Psychedelics before and during the COVID-19 Pandemic in Poland
Psychedelics show different seasonal patterns in Poland, with some correlating to school breaks or holidays, and the COVID-19 pandemic influenced some changes in these trends.
Observational Study
Rigorous JournalUse of Marijuana in the Haight-Ashbury Subculture
The use of marijuana in the Haight-Ashbury subculture has been linked to increased risk of psychosis and increased risk of drug-related arrests.
THC-O-Acetate: Scarce Evidence for a Psychedelic Cannabinoid.
THC-O-acetate (THC-Oac) shows limited evidence for psychedelic effects, with few cognitive distortions and few visuals or hallucinations, and may be influenced by expectations or contaminants.
Observational StudyPsychedelic Drug Legislative Reform and Legalization in the US.
Psychedelic drug legislative reform in the US is rapidly progressing, with most bills proposing decriminalization, but little guidance on medical oversight and special populations.
Long-term effects of psychedelic drugs: A systematic review
Psychedelic drugs can cause long-term changes in personality, depression, spirituality, anxiety, wellbeing, substance misuse, meditative practices, and mindfulness, with limited aversive side effects when administered properly.
Systematic Review
Highly CitedPsychedelics
Psychedelics, such as psilocybin, can provide relief for anxiety and depression, and may help treat alcohol and nicotine addiction, with potential benefits in cancer-related psychosocial distress.
Highly Cited