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Some studies suggest zinc can inhibit hair growth and prevent hair loss in certain conditions, while other studies indicate it is effective in treating hair loss disorders and improving hair health in individuals with low zinc levels.
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Zinc is often used to treat hair loss, even in individuals without a zinc deficiency. Research using a mouse model has shown that high doses of oral zinc can significantly inhibit hair growth by delaying the development of the anagen phase, which is the active growth phase of hair follicles. However, zinc also prolongs the catagen phase, the regression phase where hair growth ceases and follicles shrink. Interestingly, zinc treatment can accelerate the regrowth of hair after chemotherapy-induced damage, although prolonged use may retard hair regrowth.
Zinc deficiency is linked to various dermatological conditions, including hair loss. Studies have shown that individuals with lower zinc levels in their serum, hair, and erythrocytes are more likely to suffer from conditions like atopic dermatitis (AD), which can include hair loss as a symptom. Supplementing zinc in individuals with low zinc levels has shown improvements in these conditions, suggesting that maintaining adequate zinc levels is crucial for hair health .
Zinc supplementation can effectively increase zinc levels in hair, which is a useful indicator of zinc status in the body. A study involving adolescent girls in Pakistan demonstrated that consuming zinc-biofortified wheat flour led to a significant increase in hair zinc levels over six months. This suggests that dietary zinc intake directly influences hair zinc concentrations, which can be monitored to assess the effectiveness of zinc interventions.
Beyond hair health, zinc has numerous pharmacological uses in dermatology due to its antioxidant and immunomodulatory properties. It is effective in treating various skin conditions such as acne vulgaris, leishmaniasis, and hidradenitis suppurativa. These properties also contribute to its role in managing hair loss disorders, particularly in individuals with zinc deficiency.
Zinc plays a multifaceted role in hair health, influencing hair growth cycles, mitigating hair loss, and improving conditions associated with zinc deficiency. While high doses of zinc can have ambivalent effects on hair growth, maintaining adequate zinc levels through diet or supplementation is beneficial for overall hair health. Further research is needed to fully understand the optimal use of zinc in treating hair loss and other dermatological conditions.
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