Kava shows promise in treating generalized anxiety, but more studies are needed to compare its efficacy and safety compared to established pharmaceutical comparators.

Kava: A Comprehensive Review of Efficacy, Safety, and Psychopharmacology

Kava extract, when taken short-term at recommended doses, appears to be well-tolerated for anxiety treatment, but serious adverse events have been reported.

A Systematic Review of the Safety of Kava Extract in the Treatment of Anxiety

Kava kava extracts show potential for drug interactions and potentiation of other compounds' toxicity, but their risk-to-benefit ratio remains good compared to other anxiety treatments.

Kava kava: examining new reports of toxicity.

Kava products were banned in unlicensed medicines in the UK due to a risk of liver damage in rare cases.

The safety of kava: a regulatory perspective.

Kava Kava is an effective short-term treatment for anxiety symptoms, but not a replacement for prolonged anti-anxiety use, with liver toxicity potentially occurring if taken longer than 8 weeks.

The effectiveness and safety of Kava Kava for treating anxiety symptoms: A systematic review and analysis of randomized clinical trials.

Kava shows promising potential as a short-term treatment for generalized anxiety disorder, but current evidence is insufficient to confirm its effectiveness beyond placebo.

Kava for Generalized Anxiety Disorder: A Review of Current Evidence.

This paper argues that many adverse events attributed to kava are not due to the herb itself, and proposes simple measures to ensure safe kava preparations remain available in the UK.

Kava--the unfolding story: report on a work-in-progress.

Kava-kava products should be extracted with glutathione to reduce hepatotoxicity and protect against side effects.

Kava lactones and the kava-kava controversy.

Kava extracts are generally safe, but rare hepatotoxic side effects should be monitored and treated as soon as possible.

Kava extracts: safety and risks including rare hepatotoxicity.

Kava-kava effectively reduces anxiety without affecting reaction time or cognitive processing, but high doses for extended periods may cause potential side effects.

Kava-kava and anxiety: growing knowledge about the efficacy and safety.

The debate over kava safety involves cultural, social, and political factors, influencing the production of scientific knowledge and the assessment of benefit/risk posed by foods.

Tradition and toxicity: Evidential cultures in the kava safety debate

Kava extract significantly reduces anxiety symptoms compared to placebo in randomized, double-blind, placebo-controlled trials.

Kava extract versus placebo for treating anxiety

Kava's hepatotoxicity may result from inflammation, and pharmacogenomics may influence the severity of this response.

Toxicokinetics of Kava

Kava is a popular dietary supplement for anxiety and insomnia, but its safety and effectiveness in managing these conditions require further research and clinical trials.

Is Kava Safe to Be Used by the Public

The German court has lifted the ban on kava products, reaffirming its safety and highlighting the need for a comprehensive presentation of facts and misconceptions regarding kava and related drug quality issues.

German Kava Ban Lifted by Court: The Alleged Hepatotoxicity of Kava (Piper methysticum) as a Case of Ill-Defined Herbal Drug Identity, Lacking Quality Control, and Misguided Regulatory Politics

Kava has potential anti-inflammatory and anticancer effects, but more research is needed to address potential risks and ensure quality control.

Kava as a Clinical Nutrient: Promises and Challenges

A uniform, internationally accepted kava quality standardization code is needed for safe human use of kava as relaxing beverages, anxiolytic drugs, and recreational dietary supplements.

Proposal for a kava quality standardization code.

Advances in analytical techniques can detect unsuitable cultivars and raw material in kava, but a simple colorimetric test is more cost-efficient for local traders and exporters.

Recent advances in the quality control of kava, the traditional beverage of the Pacific Islands

Kava effectively treats tension and anxiety, but may have potential risks for severe motor and psychiatric responses.

The Neurobehavioural Effects of Kava

Kava, a traditional Oceanic beverage, has a central role in everyday life in the islands it is cultivated on, with a growing body of literature providing a comprehensive overview of the subject.

Kava: an overview.

Some studies suggest Kava kava is effective and well-tolerated for short-term anxiety treatment, while other studies highlight potential risks such as liver toxicity and drug interactions, especially with prolonged use.