Launching live
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Launching Live: Insights from Recent Research
DNA-Launched Live-Attenuated Vaccines
Innovative Vaccine Platform
A novel vaccine platform has emerged that utilizes DNA immunization to launch live-attenuated virus vaccines directly in vivo. This technology has been particularly effective against positive-strand RNA viruses, such as alphaviruses and flaviviruses, which have significant global public health impacts. The DNA-launched vaccine involves a recombinant plasmid encoding the full-length genomic RNA of a live-attenuated virus, positioned downstream from a eukaryotic promoter. Upon administration, the genomic RNA is transcribed and initiates limited replication of the live-attenuated virus within the recipient's tissues, thereby inducing a protective immune response. This method combines the strengths of reverse genetics, DNA immunization, and live-attenuated vaccines, offering increased safety, reduced chances of genetic reversions, and improved immunization efficacy1.
Launching into Individual Supported Living for Young Adults with Intellectual Disabilities
Transition Challenges and Support Needs
The transition to individual supported living, known as "launching," is a significant milestone for young adults with intellectual disabilities and their families. Research involving two case studies in Western Australia highlighted the stress experienced by parents during this period. The young adults gained independence gradually, heavily influenced by parental involvement. However, social isolation emerged as a major issue, and parents expressed a need for more formal support. The study concluded that families require long-term assistance to prepare for launching, and parents may need reassurance as they step back from their caregiving roles. Additionally, there is a need for better support systems to help young adults with intellectual disabilities develop friendships and social networks2.
Midlife Mothers' Experience of Launching a Child
Emotional and Developmental Journey
The process of launching a child into adulthood is a profound experience for midlife mothers. A phenomenological study involving 14 midlife mothers revealed several key themes, including the mothers' own launching, the maturational imperative, the breaking of the branch, letting go, family ties, and a mother's metamorphosis. This transition spans a prolonged developmental period for both mother and child, marked by a series of events that culminate in the child's adult status. The internal process of launching, characterized by considerable emotional pain, paradoxically leads to a sense of rebirth for the mother3.
Business Models and Challenges in Live Streaming Entertainment
Success and Challenges of YY Live
Live streaming entertainment services have seen a significant rise in popularity, with platforms like YY Live in China leading the market. Unlike Western platforms such as Facebook Live and Amazon Twitch, which rely on advertising revenue, YY Live's business model is based on viewers purchasing virtual gifts. This model has been well-received on Wall Street, highlighting its success. However, the industry faces several challenges, including the dynamics between hosts and host unions and the psychological impact of the gift-giving model. Understanding these challenges is crucial for the continued success and sustainability of live streaming services4.
Motivational Factors for Live Streamers on Twitch
Research on live streamers' continuance broadcasting intentions on Twitch has identified key motivational factors using self-determination theory. Both intrinsic and extrinsic motivations significantly influence streamers' performance expectancies, which in turn affect their perceived website attractiveness. However, perceived website attractiveness does not directly influence continuance intentions. This suggests that efforts to enhance website attractiveness should focus on improving performance expectancies. These insights provide valuable managerial implications for live streaming platforms aiming to enhance service design and better understand streamers' behavioral intentions5.
Conclusion
The concept of "launching" spans various domains, from innovative vaccine platforms to the transition of young adults with intellectual disabilities into independent living, and the emotional journey of midlife mothers. Additionally, the business models and motivational factors driving live streaming services highlight the diverse applications and challenges associated with launching in different contexts. Understanding these insights can inform better practices and support systems across these fields.
Sources and full results
Most relevant research papers on this topic
DNA-launched live-attenuated vaccines for biodefense applications
DNA-launched live-attenuated vaccines offer reduced genetic reversions, increased safety, and improved immunization for biodefense applications against positive-strand RNA viruses.
Launching: The experiences of two young adults with intellectual disability and their families in transition to individual supported living†
Families need long-term assistance to prepare for launching, and young adults with intellectual disabilities need support to develop friendships during the transition to individual supported living.
The Meaning of Launching a Child
Launching a child is an internal process achieved through pain, leading to a mother's sense of rebirth.
Observational StudyThe Business Model of Live Streaming Entertainment Services in China and Associated Challenges for Key Stakeholders
Live streaming entertainment services in China, like YY Live, rely on viewers buying virtual gifts, but face challenges in host partnerships and the psychological impact of the gift-giving model.
Determinants of live streamers' continuance broadcasting intentions on Twitch: A self-determination theory perspective
Intrinsic and extrinsic motivations significantly influence performance expectancies, but not perceived website attractiveness, which ultimately affects live streamers' continuance broadcasting intentions on Twitch.
Observational Study
Highly CitedWorldwide detection of rocket launches for space missions using International Monitoring System infrasound arrays
Infrasound arrays can detect rocket launches from thousands of kilometers away, enabling accurate identification of space missions and their parameters.
Launch Strategy, Launch Tactics, and Demand Outcomes
This paper presents a conceptual framework to help managers prioritize and integrate strategic and tactical options in product launches, aiming to maximize market acceptance.
Highly CitedLaunch activities and timing in new product development
This paper summarizes the literature on launch timing and activities, highlighting the importance of these factors for new product performance and providing inspiration for future research in the field.
Literature Review