Lump on inner thigh cancer
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Lump on Inner Thigh: Cancer Concerns and Differential Diagnoses
Introduction
A lump on the inner thigh can be alarming, especially when considering the possibility of cancer. This article synthesizes research findings on various conditions that can present as a lump in the inner thigh, including both benign and malignant possibilities.
Benign Tumors: Hemosiderotic Fibrolipomatous Tumor and Masson Tumor
Hemosiderotic Fibrolipomatous Tumor
A hemosiderotic fibrolipomatous tumor is a rare benign tumor that can present as a lump in the inner thigh. In one case, a 74-year-old woman with a history of melanoma presented with a painful swelling in her inner left thigh. Imaging via FDG PET/CT showed increased FDG activity around the lump, suggesting a possible malignancy. However, post-surgical pathological examination confirmed it to be a hemosiderotic fibrolipomatous tumor, a benign condition.
Masson Tumor
Another benign condition that can present similarly is a Masson tumor, a rare vascular lesion. A 39-year-old woman presented with a swelling on her left inner thigh, initially suspected to be a lipoma. During surgery, it was found to be a vascular tumor arising from the great saphenous vein. Histological examination confirmed it as a Masson tumor, characterized by endothelial hyperplasia and papillary structures. It is crucial to distinguish this benign tumor from malignant angiosarcoma.
Malignant Tumors: Melanoma
Giant Melanoma
Melanoma is a serious malignant tumor that can also present as a lump on the inner thigh. A case study described a 37-year-old woman with a giant black mass on her inner right thigh. She had a history of nodular melanoma excised 10 months prior and had been under homeopathic treatment since then. The delay in proper medical follow-up led to the development of a life-threatening giant melanoma.
Metastatic Disease
In another case, a 76-year-old woman presented with a bluish-purple lump in her upper medial left thigh. Initially appearing as a flat rash, it developed into a mass over two months. PET-CT imaging showed a soft tissue mass with a Standardized Uptake Value of 4, indicating potential malignancy. A biopsy was performed to determine the nature of the lesion.
Conclusion
Lumps on the inner thigh can be caused by a variety of conditions, ranging from benign tumors like hemosiderotic fibrolipomatous tumors and Masson tumors to malignant conditions such as melanoma. Accurate diagnosis through imaging and histological examination is crucial for appropriate treatment. Early medical intervention is essential, especially in cases with a history of malignancy, to prevent life-threatening complications.
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