Is Mangosteen Juice safe?

Introduction

Mangosteen juice, derived from the tropical fruit Garcinia mangostana, is widely consumed for its purported health benefits. However, its safety profile has been a subject of investigation due to potential adverse effects and varying nutritional qualities.

Key Insights

Adverse Effects:
- Severe lactic acidosis has been associated with the use of mangosteen juice as a dietary supplement.
Nutritional and Microbial Safety:
- Non-industrial fresh mango juice (NFMJ) is safe to consume within specific time frames depending on storage temperature, but this study does not directly address mangosteen juice.
- Commercially available mango juices in Bangladesh were found to be safe in terms of nutritional and microbial content, but this study also does not directly address mangosteen juice.
Health Benefits and Efficacy:
- Mangosteen juice fermented with Lactobacillus strains showed high acceptability and taste scores, along with good antioxidant activity and potential toxicity to colon tumor cells.
- Acute supplementation of mangosteen juice did not alleviate physical fatigue during exercise.
- Mangosteen rind juice showed potential antidiabetic effects by lowering blood sugar levels and improving pancreatic histology in rats.

Conclusion

While mangosteen juice has shown some potential health benefits, such as antioxidant properties and antidiabetic effects, there are significant safety concerns, including the risk of severe lactic acidosis. Therefore, caution is advised when consuming mangosteen juice, especially as a dietary supplement. Further research is needed to fully understand its safety profile and health implications.

Is Mangosteen Juice safe?

Summary

Introduction

Key Insights

Conclusion

Sources and full results

Severe lactic acidosis associated with juice of the mangosteen fruit Garcinia mangostana.

Mangosteen fruit juice, marketed as a dietary supplement, can cause severe lactic acidosis in some individuals.

Shelf life of non-industrial fresh mango juice: Microbial safety, nutritional and sensory characteristics

Non-industrial fresh mango juice can be safely consumed within 8 hours at 4, 25 and 37°C, with good quality maintained within 2 hours at 4 or 25°C.

Probiotic Beverage from Mangosteen Juice Fermented with Lactobacillus Strains

Mangosteen juice fermented with Lactobacillus strains has high acceptability and taste, but may have higher toxicity to colon tumor cells than unfermented mangosteen juice.

Physicochemical and Microbiological Qualities’ Assessment of Popular Bangladeshi Mango Fruit Juice

Locally available mango juices in Bangladesh contain a safe level of nutritional and microbial elements for human consumption, but not highly satisfactory.

Acute Garcinia mangostana (mangosteen) supplementation does not alleviate physical fatigue during exercise: a randomized, double-blind, placebo-controlled, crossover trial

Acute mangosteen supplementation does not alleviate physical fatigue during exercise, except for a positive impact on mood states.

The Effect of Juice Mangosteen Rind (Garcinia Mangostana L.) to Blood Sugar Levels and Histological of Pancreatic Rats With The Induction of Streptozotocin

Juice mangosteen rind can effectively improve blood sugar levels and pancreatic histological conditions in rats with streptozotocin-induced diabetes mellitus.

Evaluation of Mangosteen juice blend on biomarkers of inflammation in obese subjects: a pilot, dose finding study

A proprietary mangosteen juice blend (XanGo JuiceTM) reduced CRP levels in obese individuals compared to placebo, but other inflammation markers and lipid peroxidation markers showed no significant differences.

Mangosteen Pericarp and Its Bioactive Xanthones: Potential Therapeutic Value in Alzheimer’s Disease, Parkinson’s Disease, and Depression with Pharmacokinetic and Safety Profiles

Mangosteen pericarp and its bioactive xanthones show potential therapeutic value in Alzheimer's, Parkinson's, and depression, with potential benefits from neuroprotective, antioxidant, and anti-neuroinflammatory effects.

Antioxidant capacity and antibacterial activity of different parts of mangosteen (Garcinia mangostana Linn.) extracts

Mangosteen waste, particularly the pericarp, demonstrates high antioxidant capacity and antibacterial activity, potentially benefiting the food industry as a bio-preservative.

Xanthones in mangosteen juice are absorbed and partially conjugated by healthy adults.

Mangosteen juice's xanthones are absorbed and partially conjugated in healthy adults when ingested with a high-fat meal, but their release from pericarp particles during digestion may be limited.

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