Medication for tummy ache
Pro Research Analysisby 
Searched over 200M research papers
Effective Medications for Tummy Ache Relief
Antihistamines for Stomach Pain Relief
Antihistamines, commonly known for their use in treating allergies, have also been found to alleviate stomach pain. These medications work by blocking histamine receptors, which can reduce inflammation and discomfort in the gastrointestinal tract. For instance, histamine H1 receptor antagonists like ebastine have shown efficacy in managing visceral pain, including that associated with irritable bowel syndrome (IBS)2. This suggests that antihistamines could be a viable option for those experiencing stomach aches due to various causes.
Pharmacological Treatments for IBS-Related Abdominal Pain
Irritable Bowel Syndrome (IBS) is a common condition that often results in abdominal pain. Several pharmacological treatments have been identified to manage this pain effectively. These include:
- Antispasmodics: These medications help to relax the muscles of the gastrointestinal tract, reducing spasms and pain.
- Peppermint Oil: Known for its soothing properties, peppermint oil can help alleviate IBS symptoms.
- Antidepressants: Tricyclic antidepressants and selective serotonin reuptake inhibitors (SSRIs) can modulate pain perception and improve symptoms.
- 5-HT3 Receptor Antagonists: Medications like alosetron, ondansetron, and ramosetron can reduce pain by blocking serotonin receptors in the gut.
- Non-Absorbed Antibiotics: Rifaximin is used to alter gut flora, which can help reduce IBS symptoms.
- Secretagogues: Lubiprostone and linaclotide can increase fluid secretion in the intestines, easing stool passage and reducing pain.
- Opioid Receptor Modulators: Eluxadoline acts on opioid receptors to reduce pain and diarrhea.
- GABAergic Agents: Gabapentin and pregabalin can help manage pain by affecting neurotransmitter activity2.
These treatments have been supported by various clinical trials and meta-analyses, demonstrating their efficacy and safety in managing IBS-related abdominal pain2.
Biling Weitong Granules for Stomach Ache Disorders
Biling Weitong Granules, a traditional Chinese medicine, have been evaluated for their effectiveness in treating stomach ache disorders. A systematic review and meta-analysis of 27 randomized controlled trials (RCTs) involving 2,902 participants found that these granules significantly improved visual analogue scale (VAS) scores and stomach ache disorder symptom scores compared to conventional Western medicine or placebo. Additionally, they showed a higher clinical recovery rate and Helicobacter pylori eradication rate3.
The safety profile of Biling Weitong Granules was also favorable, with common adverse events being mild and including nausea, vomiting, rash, diarrhea, loss of appetite, and a bitter taste in the mouth. No serious adverse events were reported, making it a promising option for those seeking alternative treatments for stomach ache disorders3.
Conclusion
In summary, various medications can effectively manage tummy aches, depending on the underlying cause. Antihistamines like ebastine can reduce inflammation and pain, while a range of pharmacological treatments are available for IBS-related abdominal pain, including antispasmodics, peppermint oil, antidepressants, and more. Additionally, traditional remedies like Biling Weitong Granules have shown promise in clinical studies. Always consult with a healthcare provider to determine the most appropriate treatment for your specific condition.
Sources and full results
Most relevant research papers on this topic
Antihistamine for the pain in your stomach
You know that last piece of chocolate cake or that last slice of pizza the one you know you really shouldn't have eaten -but you wouldn't have forgiven yourself if you walked past it! Well, now you're paying for it with the stomach cramping, tummy ache, bloating...
Dietary and pharmacological treatment of abdominal pain in IBS
Dietary measures and pharmacological treatments, such as antispasmodics and 5-HT3 receptor antagonists, can effectively relieve abdominal pain in IBS patients.
Systematic Review
Rigorous Journal
Highly Cited[Systematic review and Meta-analysis of Biling Weitong Granules in treatment of stomach ache disorder].
Biling Weitong Granules effectively improve stomach ache disorder symptoms, clinical recovery rate, and Helicobacter pylori eradication rate, with good safety and no serious adverse reactions.
Meta-AnalysisThe use of a combined herbal remedy for some functional bowel diseases is the implementation of the concept of multitarget therapy
Tummy ease is an effective and safe alternative therapy for patients with functional constipation and IBS-C, improving gastrointestinal symptoms and quality of life.
In vivo gastroprotective effects of five Turkish folk remedies against ethanol-induced lesions.
Turkish folk remedies, including roots, herbs, and fruits, show significant stomach protection against ethanol-induced gastric ulcers in rats.
Non-RCT
Animal StudyHighly CitedTreatment of abdominal pain in irritable bowel syndrome
TCAs, a low-FODMAP diet, and antispasmodics are effective in reducing abdominal pain and improving bowel patterns in irritable bowel syndrome patients.
Literature ReviewRigorous JournalNatural remedies effective on stomachache in traditional medicine
Persian medicinal plants, such as Panicum miliaceum, Punica granatum, Solanum nigrum, Calicotome spinosa, Tamarindus indica, Cuminum cyminum, Prunus domestica, Matricaria recutita, Viola
Literature ReviewClinical Study about the Ache Caused by Stomach Tumor Treated with Jiaweibaoankeli
Jiaweibaoankeli is an effective and safe medication for easing stomach ache caused by stomach tumor, improving living quality without side effects or toxicity.
RCT[Giardiasis as a rare disorder in differential diagnosis of abdominal pain].
Giardiasis is a rare but important diagnosis for children with nonspecific abdominal pain, especially when usual therapy fails.
Case ReportPain in irritable bowel syndrome: Does anything really help?
Anti-neuropathic agents like amitriptyline, pregabalin, gabapentin, and duloxetine show promise in relieving abdominal pain and improving quality of life in patients with irritable bowel syndrome.
Systematic ReviewRigorous Journal