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These studies suggest that various imaging and diagnostic techniques, including human back templates, SPECT/CT, photoacoustic imaging, intelligent systems, and multi-direction 3D color-texture features, improve the accuracy and early detection of melanoma, particularly on the back.
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Melanoma, a highly fatal type of skin cancer, often appears on the back in men, making early detection crucial for effective treatment. The back is a common site for melanoma due to its occasional sun exposure, which can lead to the development of pigmented skin lesions (PSLs) that may become malignant .
Total body photography is advocated for high-risk patients to monitor changes in PSLs, which is essential for early melanoma detection. However, manual inspection of these images is subjective and error-prone. A computer program that tracks PSLs can significantly improve accuracy. Researchers have developed a human back template (atlas) to facilitate spatial normalization of PSLs, using landmarks such as the neck, shoulder, armpit, and hip points. This method improves the accuracy of PSL matching by overlaying a grid on back images and registering it into a unit-square rectilinear grid.
Photoacoustic imaging, combined with ultrasound, offers a promising non-invasive diagnostic tool for melanoma. This technique uses dual-wavelength acoustic-resolution-based photoacoustic microscopy to achieve high-contrast detection of melanin molecules in tissues. It allows for accurate positioning of melanoma and surrounding normal tissues, enhancing early diagnosis and treatment.
Sentinel node mapping is crucial for staging melanoma and planning treatment. SPECT/CT imaging helps differentiate between true and false in-transit lymph nodes, which can be mistaken for metastasis. This technique improves the accuracy of sentinel node biopsies, aiding in better management of melanoma on the back.
Distinguishing melanoma from nevus is challenging due to their similar visual appearances. An intelligent system using image processing techniques, such as Gaussian filtering and K-mean clustering, has been developed to segment and classify skin lesions. This system uses a support vector machine (SVM) for classification, achieving high accuracy in distinguishing melanoma from nevus.
A novel method for feature extraction from dermoscopic images, termed multi-direction 3D color-texture feature (CTF), has been proposed. This method, combined with a back propagation multilayer neural network classifier, has shown high accuracy, sensitivity, and specificity in detecting melanoma. The technique has been tested on the PH2 dataset, demonstrating improved results over existing methods.
A patient-centric dataset has been created to address the need for patient-level information in melanoma diagnosis. This dataset includes multiple skin lesions from the same patient, allowing for holistic judgment by dermatologists. It provides identifiers for mapping lesions to the same patient, which is crucial for ruling out false positives in patients with many atypical nevi. This approach aligns with clinical practices and enhances the accuracy of melanoma detection.
Early detection of melanoma on the back is vital for effective treatment. Advances in imaging techniques, such as photoacoustic and ultrasound imaging, along with intelligent classification systems, are improving the accuracy and efficiency of melanoma diagnosis. The development of patient-centric datasets further supports clinicians in making informed decisions, ultimately leading to better patient outcomes.
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