metabolities isolated from eruca stiva

Introduction

Eruca sativa, commonly known as rocket or arugula, is a leafy green vegetable known for its peppery flavor and nutritional benefits. It contains a variety of bioactive compounds, including glucosinolates, flavonoids, and other secondary metabolites, which contribute to its health-promoting properties.

Key Insights

Glucosinolates and Their Hydrolysis Products:
- Eruca sativa contains significant levels of glucosinolates such as 4-methylthiobutylglucosinolate, 4-mercaptobutylglucosinolate, and 4-methylsulfinylbutylglucosinolate in its leaves, seeds, and flowers .
- The hydrolysis products of these glucosinolates, including isothiocyanates like erucin and 4-(mercapto)butyl isothiocyanate, are also present and have been linked to various health benefits .
Flavonoids:
- The leaves of Eruca sativa are rich in flavonoids, particularly quercetin derivatives such as quercetin 3,3',4'-tri-O-β-D-glucopyranoside and kaempferol-3,4'-di-O-β-glucoside .
- These flavonoids contribute to the plant's antioxidant properties and potential health benefits .
Antioxidant Activity:
- Eruca sativa exhibits significant free-radical scavenging activity, particularly against hydroxyl radicals, due to its glucosinolate and isothiocyanate content.
Antihypertensive Effects:
- The methanolic extract of Eruca sativa has been shown to induce a significant reduction in mean arterial pressure in both normotensive and hypertensive rats, likely due to its vasodilatory effects mediated by muscarinic receptors and nitric oxide release.
Metabolite Profiling:
- Advanced metabolomic approaches have identified a variety of bioactive compounds in Eruca sativa, including glucosinolates, glycosylated flavonoids, fatty acids, and lipids. These profiles can vary based on geographical cultivation areas.

Conclusion

Eruca sativa is a rich source of bioactive compounds, particularly glucosinolates and flavonoids, which contribute to its health-promoting properties. These compounds exhibit significant antioxidant activity and potential antihypertensive effects. The metabolite profile of Eruca sativa can vary based on its geographical origin, highlighting the importance of cultivation conditions in determining its nutritional and therapeutic value.

Metabolities isolated from eruca stiva

Summary

Introduction

Key Insights

Conclusion

Sources and full results

Ontogenic profiling of glucosinolates, flavonoids, and other secondary metabolites in Eruca sativa (salad rocket), Diplotaxis erucoides (wall rocket), Diplotaxis tenuifolia (wild rocket), and Bunias orientalis (Turkish rocket).

Eruca sativa, Diplotaxis tenuifolia, and Bunias orientalis contain significant amounts of glucosinolates, flavonoids, and vitamins, with their phytochemical profiles varying by ontogenic stage.

The Eruca sativa Genome and Transcriptome: A Targeted Analysis of Sulfur Metabolism and Glucosinolate Biosynthesis Pre and Postharvest

The Eruca sativa genome reveals diverse gene expression patterns regulating sulfur metabolism, glucosinolate biosynthesis, and glutathione biosynthesis, with one breeding line maintaining GSL accumulation and hydrolysis product formation throughout storage.

Quercetin 3,3', 4'-tri-O-β-D-glucopyranosides from leaves of Eruca sativa (Mill.)

Quercetin 3,3′,4′-tri-O--D-glucopyranosides from Eruca sativa leaves show potential as a promising anti-inflammatory agent.

Probing the free-radical scavenging activity of the extract, the major glucosinolate and isothiocyanate of Eruca sativa Mill. and Lepidium densiflorum Schrad. seeds

The compounds isolated from Lepidium densiflorum and Eruca sativa seeds were not very efficient antioxidants, with 4-HBITC being more effective than SNB for scavenging DPPH and OH radicals.

Identification of Bis(4-isothiocyanatobutyl) Disulfide and Its Precursor from Rocket Salad (Eruca sativa)

The compound bis(4-isothiocyanatobutyl) disulfide, found in Rocket salad (Eruca sativa), was identified and synthesized by oxidizing 4-(mercapto)butyl isothiocyanate, a glucosinolate breakdown

Antihypertensive effect of the methanolic extract from Eruca sativa Mill., (Brassicaceae) in rats: Muscarinic receptor-linked vasorelaxant and cardiotonic effects.

The methanolic extract from Eruca sativa Mill., (Brassicaceae), has a muscarinic receptor-linked antihypertensive effect in rats, supporting its traditional use in hypertension treatment.

Chemical Analysis of Eruca sativa Ethanolic Extract and Its Effects on Hyperuricaemia

The ethanolic extract of Eruca sativa leaves shows potential in treating hyperuricaemia and its comorbidities, with kaempferol-3,4′-di-O--glucoside as a key component responsible for its activity.

Determination of glucosinolates and phenolic compounds in rocket salad by HPLC-DAD–MS: Evaluation of Eruca sativa Mill. and Diplotaxis tenuifolia L. genetic resources

Rocket salad species Eruca sativa and Diplotaxis tenuifolia show qualitative differences in polyphenol profiles, with kaempferol derivatives being more abundant in Eruca samples and quercetin derivatives in Diplotaxis samples.

The Eruca sativa Genome and Transcriptome: A Targeted Analysis of Sulfur Metabolism and Glucosinolate Biosynthesis Pre and Postharvest

The Eruca sativa genome reveals diverse gene expression patterns regulating sulfur metabolism and glucosinolate biosynthesis, with one breeding line maintaining GSL accumulation and hydrolysis product formation throughout storage.

Metabolite Profiling for Typization of “Rucola della Piana del Sele” (PGI), Eruca sativa, through UHPLC-Q-Exactive-Orbitrap-MS/MS Analysis

"Rucola della Piana del Sele" (PGI) Eruca sativa grown in Piana del Sele has a unique metabolite profile, with higher levels of glycosylated quercetin and erucin, compared to other cultivars and spontaneously

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