RT-PCR and EBV-VL measurements may aid in early diagnosis, and antiviral agents may be useful treatments for severe infectious mononucleosis.

Current diagnosis and management of infectious mononucleosis

Steroids show potential for short-term symptom control in infectious mononucleosis, but more research is needed to confirm their effectiveness and safety.

Steroids for symptom control in infectious mononucleosis.

Acyclovir combined with prednisolone effectively inhibited oropharyngeal Epstein-Barr virus replication in infectious mononucleosis patients without affecting clinical symptoms or developing EBV-specific cellular immunity.

Acyclovir and prednisolone treatment of acute infectious mononucleosis: a multicenter, double-blind, placebo-controlled study.

Chinese herbs effectively and safely treat children's infectious mononucleosis, improving clinical symptoms and showing a certain effect on immune regulation.

Clinically controlled study on children’s infectious mononucleosis treated by Chinese medicine

Antiviral agents may be considered as an adjunct to steroid treatment for severe EBV infections in immunocompetent patients.

Antiviral treatment for severe EBV infections in apparently immunocompetent patients.

Infectious mononucleosis symptoms subside in three to five days, and recovery time varies depending on the patient's age and activity level.

How I Manage Infectious Mononucleosis

Activity and early bed rest can speed recovery from infectious mononucleosis, while drug therapy shows no evidence of shortening recovery time.

Recovery from infectious mononucleosis: a case for more than symptomatic therapy? A systematic review.

Steroids for symptom control in infectious mononucleosis have not been consistently shown to be effective, with insufficient evidence and poor trial quality to recommend their routine use.

No new evidence to support the routine use of steroids in the treatment of infectious mononucleosis

Return-to-play decisions for athletes with infectious mononucleosis need to be individualized due to variable disease course and lack of evidence-based guidelines.

Return to Play After Infectious Mononucleosis

Infectious mononucleosis is caused by Epstein-Barr virus (EBV) and can lead to long-term complications like Hodgkin lymphoma and multiple sclerosis.

Infectious mononucleosis

Infectious mononucleosis is a viral infection with symptoms ranging from sore throat to fatigue, adenopathy, and atypical lymphocytosis.

Epstein-Barr virus infectious mononucleosis.

Epstein-Barr virus can cause early complications like hepatitis, splenic rupture, and airway compromise, and may increase the risk of lymphoproliferative cancers, multiple sclerosis, and chronic active Epstein-Barr virus infection.

Epstein-Barr virus and its association with disease - a review of relevance to general practice

A systematic approach to laboratory evaluation and return to play decisions can minimize clinical variation and help minimize potential splenic rupture complications in athletes with infectious mononucleosis.

Infectious Mononucleosis Management in Athletes.

Antiviral therapy may be effective in preventing viral replication and improving recovery time in infectious mononucleosis patients, but more research is needed.

Antiviral agents for infectious mononucleosis (glandular fever).

Infectious mononucleosis in young athletes presents difficult return-to-play decisions, and there are currently no evidence-based guidelines for their management.

Mononucleosis and Athletic Participation: An Evidence-Based Subject Review

Prolonged steroid use in uncomplicated infectious mononucleosis cases can lead to severe complications, such as septic shock and orbital cellulitis.

Severe Complications From Infectious Mononucleosis After Prolonged Steroid Therapy.

Azathioprine treatment for Crohn's disease may contribute to fatal infectious mononucleosis, requiring careful monitoring and consideration in patients with inflammatory bowel disease.

Fatal infectious mononucleosis: a severe complication in the treatment of Crohn's disease with azathioprine.

Antibacterial drugs, especially ampicillin, can cause rashes in infectious mononucleosis patients, suggesting that they should not be used for acute sore throats except in sensitive patients.

Hypersensitivity reactions to antibacterial drugs in infectious mononucleosis.

Corticosteroids show small and inconsistent benefits for symptom relief in children with infectious mononucleosis, and should be reserved for severe cases.

Corticosteroids for infectious mononucleosis

The treatment of infectious mononucleosis remains symptomatic until the causative agent is identified, with significant advances in managing complications.

The treatment of infectious mononucleosis.

Some studies suggest antiviral agents, steroids, and Chinese herbs may be useful in treating infectious mononucleosis, while other studies emphasize rest and activity management without consistent evidence supporting drug therapy.