How much Garlic should I take daily?

Introduction

Garlic is a common dietary supplement known for its potential health benefits, including its effects on inflammation, immunity, and cardiovascular health. However, the appropriate daily intake of garlic to maximize these benefits without adverse effects is a subject of scientific investigation.

Key Insights from Research Papers

Daily supplementation with 3.6 grams of aged garlic extract (AGE) can reduce chronic inflammation and improve immune function in adults with obesity, as well as lower blood LDL concentration.
Consuming one clove of fresh garlic (approximately 3 grams) daily for an extended period can lead to a reduction in serum cholesterol and thromboxane, which may help in preventing thrombosis.
High doses of garlic can cause liver damage, with safe doses suggested to be 0.1 or 0.25 grams per kilogram of body weight per day, indicating that moderation is important to avoid hepatotoxicity.

Conclusion

The research suggests that garlic can have beneficial effects on health, particularly in reducing inflammation, improving immune function, and preventing thrombosis. A daily intake of approximately 3 grams, either as aged garlic extract or a fresh clove, appears to be effective for these purposes. However, it is crucial to consider body weight and individual health conditions, as excessive intake can lead to liver damage. Therefore, moderate consumption within the range of 0.1 to 0.25 grams per kilogram of body weight is recommended to ensure safety.

How much Garlic should I take daily?

Summary

Introduction

Key Insights from Research Papers

Conclusion

Sources and full results

Aged garlic extract supplementation modifies inflammation and immunity of adults with obesity: A randomized, double-blind, placebo-controlled clinical trial.

Daily aged garlic extract supplementation for 6 weeks can reduce chronic inflammation and improve immune function in adults with obesity, potentially preventing chronic diseases linked to low-grade inflammation.

Consumption of a garlic clove a day could be beneficial in preventing thrombosis.

A single garlic clove daily for 26 weeks can reduce serum cholesterol and thromboxane levels, potentially aiding in preventing thrombosis.

Garlic hepatotoxicity: safe dose of garlic.

High doses of garlic can cause liver damage, while low doses (0.1 or 0.25 g/kg body weight/day) are safe for human consumption.

Effects of crude garlic extract on mouse chromosomes in vivo.

A low concentration of garlic extract daily for at least 30 days can effectively protect against the clastogenic effects of known genotoxicants.

Effect of short-term administration of garlic supplements on single-dose ritonavir pharmacokinetics in healthy volunteers.

Short-term dosing of garlic supplements over 4 days did not significantly alter the single-dose pharmacokinetics of ritonavir in healthy volunteers.

Effects of garlic (Allium sativum L.) supplementation on cytochrome P450 2D6 and 3A4 activity in healthy volunteers

Garlic extracts are unlikely to alter the disposition of medications dependent on CYP2D6 or CYP3A4 pathways in healthy volunteers.

Effect of Garlic on Total Serum Cholesterol

Oral garlic supplementation may effectively decrease serum cholesterol levels by as much as 15% to 20%, with varying treatment effects across different studies.

A randomized factorial study of the effects of long-term garlic and micronutrient supplementation and of 2-wk antibiotic treatment for Helicobacter pylori infection on serum cholesterol and lipoproteins.

Long-term garlic supplementation had no effect on lipid profiles, while micronutrient supplementation slightly increased total and LDL-cholesterol levels in a rural Chinese population.

On the effect of garlic on plasma lipids and lipoproteins in mild hypercholesterolaemia.

Garlic ingestion showed no significant effect on lipids and lipoproteins in mild hypercholesterolaemia patients.

Garlic-induced alteration in rat liver and kidney morphology and associated changes in endogenous antioxidant status.

Garlic in low doses can enhance endogenous antioxidant status, but at higher doses it can reverse these effects and cause morphological changes in the liver and kidneys.

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