How much Kava kava should I take daily?
Pro Research Analysisby 
Searched over 200M research papers
Consensus Meter
Optimal Daily Dosage of Kava Kava
Introduction to Kava Kava and Its Uses
Kava kava, derived from the plant Piper methysticum, is commonly used for its anxiolytic properties, particularly in the treatment of generalized anxiety disorder (GAD). It is favored by individuals seeking natural remedies over conventional pharmaceuticals due to its perceived safety and efficacy.
Recommended Dosage for Generalized Anxiety Disorder
Clinical Trials and Dosage Efficacy
Several clinical trials have investigated the efficacy of kava kava in treating GAD. The recommended dosage for therapeutic use ranges from 120 mg to 280 mg of kavalactones per day. This dosage has been found to be safe and well-tolerated for short-term use, typically between 4 to 8 weeks. In a randomized controlled trial, participants were administered 120 mg of kavalactones per day, with the option to increase to 240 mg per day if no response was observed. This dosage regimen was effective in reducing anxiety symptoms without significant adverse effects.
Safety and Tolerability
Kava kava has been shown to be safe for short-term use at the recommended dosages. Studies have reported no significant differences in liver function tests or adverse reactions attributable to kava. However, it is important to note that high doses, such as those equivalent to 380 mg/kg/day in animal studies, have been associated with liver enlargement and increased expression of hepatic enzymes, indicating potential liver toxicity at excessive dosages.
Considerations for Long-Term Use
Potential Adverse Effects
While kava kava is generally safe for short-term use, long-term consumption, especially at high doses, may pose risks. High levels of kava consumption, such as those observed in some Aboriginal communities, have raised concerns about liver health and other potential adverse effects. Therefore, it is crucial to adhere to the recommended dosages and consult healthcare providers for prolonged use.
Impact on Sexual Function
Interestingly, kava kava has been found to have a positive effect on sexual function, particularly in females. A study reported a significant increase in sexual drive among female participants taking kava compared to those on a placebo. This suggests that kava may have additional benefits beyond its anxiolytic properties.
Conclusion
In summary, the optimal daily dosage of kava kava for treating generalized anxiety disorder ranges from 120 mg to 280 mg of kavalactones. This dosage is effective and well-tolerated for short-term use, typically up to 8 weeks. While kava kava is generally safe, it is important to avoid high doses and consult healthcare providers for long-term use to mitigate potential risks, particularly concerning liver health.
Sources and full results
Most relevant research papers on this topic
Kava for Generalized Anxiety Disorder: A Review of Current Evidence.
Kava for the Treatment of Generalized Anxiety Disorder RCT: Analysis of Adverse Reactions, Liver Function, Addiction, and Sexual Effects
High dose of commercial products of kava (Piper methysticum) markedly enhanced hepatic cytochrome P450 1A1 mRNA expression with liver enlargement in rats.
Kava in Arnhem Land: a review of consumption and its social correlates
Kava and Valerian in the treatment of stress‐induced insomnia
Kava in the Treatment of Generalized Anxiety Disorder: A Double-Blind, Randomized, Placebo-Controlled Study
Kava for generalised anxiety disorder: A 16-week double-blind, randomised, placebo-controlled study
[Kava, kavapyrones and toxic liver injury].
Clinical efficacy of kava extract WS 1490 in sleep disturbances associated with anxiety disorders. Results of a multicenter, randomized, placebo-controlled, double-blind clinical trial.
Effects of the heavy usage of kava on physical health: summary of a pilot survey in an aboriginal community.
Try another search
What are the latest findings on the role of dietary cholesterol in heart health?
what is faster than the speed of light
meta fact checking
The implications of quantum computing for data security and encryption.
What are the ethical implications of genetic engineering?
How do we understand and model the effects of genetic modification on ecosystems?