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These studies suggest that the acceptable daily intake of licorice root for humans is 0.015-0.229 mg glycyrrhizin/kg body weight/day, while for Nile tilapia, 10 g/kg of diet is optimal.
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Licorice root, derived from the plant Glycyrrhiza sp., is widely consumed for its flavor and medicinal properties. Its main active component, glycyrrhizin, has been recognized for various pharmacological effects, but its consumption must be carefully managed due to potential adverse effects.
For human consumption, an acceptable daily intake of glycyrrhizin from licorice root is proposed to be within the range of 0.015-0.229 mg/kg body weight. This intake considers the balance between the beneficial pharmacological effects and the avoidance of adverse hypermineralocorticoid-like effects. In the context of aquaculture, a dietary inclusion level of 10 g/kg diet of licorice root powder has been found to be optimal for Nile tilapia, indicating species-specific dosage recommendations.
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