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Senna is a well-known plant-derived laxative commonly used to treat constipation. Understanding the appropriate daily dosage of senna is crucial for maximizing its benefits while minimizing potential side effects.
Maximum Tolerated Dose in Rats:
Effective Dose for Chemotherapy-Induced Constipation in Humans:
The appropriate daily dosage of senna varies depending on the context. For long-term use in rats, 300 mg/kg/day was the maximum tolerated dose. For treating chemotherapy-induced constipation in humans, a dose of 40 mg/kg was found to be both effective and safe. Always consult with a healthcare provider for personalized dosage recommendations.
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