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Pill with 123: Sodium Iodide (Na 123I) Oral Capsule
Introduction to Sodium Iodide (Na 123I)
Sodium Iodide (Na 123I) is a radioisotope commonly used in medical diagnostics, particularly for thyroid studies and detecting metastases. This radioisotope is produced through the proton bombardment of enriched Xenon-124 using a cyclotron.
Formulation and Quality Control
The production process of Na 123I involves several critical steps to ensure its purity and effectiveness. After the proton bombardment, the target is rinsed with distilled water, resulting in a clear and colorless acidic solution containing Iodine-123. To prepare Na 123I, a buffer is added to this solution to adjust the pH to 7.
Quality control measures are stringent, adhering to the standards set by the U.S. Pharmacopoeia. The Na 123I produced boasts a high radionuclide purity of 99.99% and a radiochemical purity of 98%. These high purity levels are crucial for the safety and efficacy of the diagnostic procedures in which Na 123I is used.
Capsule Preparation
The final step in the preparation involves adding the Na 123I solution to capsules pre-filled with inert powder. Each capsule contains 200 µCi of Na 123I, making them ready for use in hospital settings. This precise dosage ensures that patients receive the correct amount of the radioisotope for accurate diagnostic imaging.
Conclusion
Sodium Iodide (Na 123I) capsules are a critical tool in the diagnosis of thyroid conditions and metastases. The meticulous production and quality control processes ensure that these capsules are both safe and effective for medical use. The high purity levels of Na 123I make it a reliable choice for healthcare professionals in the field of nuclear medicine.
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