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10 papers analyzed
These studies suggest that pine bark extract is generally safe with no serious adverse effects reported.
8 papers analyzed
20 papers analyzed
Pine bark extract, derived from various species of the Pinus genus, is rich in bioflavonoids, particularly proanthocyanidins, which are known for their antioxidant properties. It is marketed for its potential benefits in treating or preventing various chronic conditions associated with oxidative stress. This synthesis aims to evaluate the safety of pine bark extract based on findings from multiple research studies.
General Safety and Toxicology:
Adverse Events:
Efficacy and Safety in Chronic Disorders:
Antioxidant and Anti-inflammatory Properties:
Based on the available research, pine bark extract appears to be safe for use as a dietary supplement and food ingredient. While its efficacy in treating various chronic conditions is not definitively proven, the absence of serious adverse effects in both animal and human studies supports its safety profile. Minor adverse events are rare and generally mild, further indicating that pine bark extract is safe for consumption.
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