10 papers analyzed
These studies suggest preeclampsia is a serious maternal endothelium disease linked to antiangiogenic factors, increased cardiovascular risks, and often requires early delivery, with ongoing research aimed at improving prevention, diagnosis, and treatment.
Preeclampsia is a pregnancy-specific disorder characterized by the onset of hypertension and proteinuria after 20 weeks of gestation. It affects 3% to 5% of pregnancies and is a leading cause of maternal and neonatal morbidity and mortality. The condition is complex, involving multiple organ systems and has significant implications for both immediate and long-term health.
Pathogenesis and Mechanisms:
Clinical Manifestations:
Risk Factors and Associations:
Long-term Health Implications:
Preeclampsia is a multifaceted disorder with significant short-term and long-term health implications. It involves complex interactions between placental dysfunction, systemic inflammation, and endothelial disruption. Women with preexisting conditions such as diabetes and vascular disease are at higher risk. The condition not only affects maternal and fetal health during pregnancy but also predisposes women to future cardiovascular and metabolic diseases, underscoring the need for lifelong monitoring and management.
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