Reduce cholesterol supplements
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Cholesterol-Lowering Supplements: An Overview
Plant Sterols and Stanols: Effective LDL Cholesterol Reduction
Plant Sterols and Stanols
Plant sterols and stanols are well-documented for their cholesterol-lowering properties. Research indicates that unesterified plant sterols and stanols can significantly reduce LDL cholesterol levels in hypercholesterolemic individuals. A study involving 15 subjects showed that diets supplemented with plant sterols, stanols, or a mixture of both resulted in LDL cholesterol reductions of 11.3%, 13.4%, and 16.0%, respectively, compared to a control group. Another study confirmed that a reduced-calorie orange juice beverage containing plant sterols significantly lowered LDL cholesterol by 9.4% and also reduced C-reactive protein (CRP) levels, a marker of inflammation. Additionally, adherence to a Mediterranean diet enhanced the cholesterol-lowering effects of plant sterols, further reducing LDL cholesterol levels.
Vitamin C: Modest Impact on LDL Cholesterol and Triglycerides
Vitamin C Supplementation
Vitamin C has also been explored for its potential to lower cholesterol. A meta-analysis of 13 randomized controlled trials found that supplementation with at least 500 mg/day of vitamin C for a minimum of four weeks resulted in a significant decrease in LDL cholesterol by 7.9 mg/dL and triglycerides by 20.1 mg/dL. However, the effect on HDL cholesterol was not significant. This suggests that while vitamin C can contribute to lowering LDL cholesterol and triglycerides, its impact on HDL cholesterol is minimal.
Red Yeast Rice: A Traditional Approach with Proven Benefits
Red Yeast Rice
Red yeast rice, a traditional Chinese supplement, has been shown to effectively lower cholesterol levels. In a study involving 83 hyperlipidemic subjects, those who consumed red yeast rice experienced significant reductions in total cholesterol and LDL cholesterol compared to a placebo group. The study highlighted that red yeast rice could be a viable food-based approach to managing cholesterol levels.
Capsaicinoids: Promising but Requires Further Validation
Capsaicinoid Supplementation
Capsaicinoids, the active compounds in chili peppers, have shown potential in lowering cholesterol levels. A meta-analysis of 10 controlled studies involving 398 participants found that capsaicinoid supplementation significantly reduced total cholesterol and LDL cholesterol levels. However, no significant effects were observed on HDL cholesterol and triglycerides. While these findings are promising, further randomized controlled trials are needed to validate the efficacy of capsaicinoids in diverse populations.
Probiotics: Beneficial for Mild Hypercholesterolemia
Probiotic Supplementation
Probiotics have also been investigated for their cholesterol-lowering effects. A meta-analysis of 11 randomized clinical trials found that probiotic supplementation significantly reduced total cholesterol and LDL cholesterol levels. The effect was more pronounced in individuals with mildly elevated cholesterol levels and with long-term probiotic use. This suggests that probiotics could be a useful addition to dietary interventions for managing cholesterol.
Conclusion
In summary, various supplements, including plant sterols and stanols, vitamin C, red yeast rice, capsaicinoids, and probiotics, have shown potential in reducing cholesterol levels. Plant sterols and stanols, in particular, have robust evidence supporting their efficacy in lowering LDL cholesterol. Vitamin C and red yeast rice also offer significant benefits, while capsaicinoids and probiotics show promise but require further research. Incorporating these supplements into a balanced diet and healthy lifestyle can be an effective strategy for managing cholesterol levels and reducing cardiovascular risk.
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