Is Rosehips safe?

Introduction

Rosehips, the fruit of the rose plant, are widely used in food, cosmetics, and traditional medicine. They are known for their high content of bioactive compounds, including polyphenols, vitamins, and antioxidants. Given their widespread use, it is important to evaluate their safety and efficacy in various applications.

Key Insights

General Safety and Tolerability
- Rosehip supplements were well tolerated and considered systemically safe in patients with osteoarthritis, showing no significant adverse effects compared to glucosamine and chondroitin sulphate.
- Rosehip seed oil was found to be safe for use in treating skin lesions in patients with type 1 diabetes, with no adverse effects recorded.
- Standardized rosehip extract showed no genotoxicity and had a no-observed-adverse-effect level greater than 1000 mg/kg in rats, indicating a high safety margin.
Anti-inflammatory and Antioxidant Properties
- Rosehip powder demonstrated significant anti-inflammatory and antioxidant activities, making it beneficial for conditions like osteoarthritis and rheumatoid arthritis without the ulcerogenic effects associated with NSAIDs.
- High levels of antioxidants, including ascorbic acid and flavonols, were found in rosehip fruits, contributing to their health benefits .
Potential Therapeutic Uses
- Rosehip extracts were effective in reducing cell proliferation in human glioblastoma cell lines, suggesting potential as a complementary treatment in cancer therapy.
- Rosehips, combined with polyphenol-active Lactobacillus strains, showed potential in preventing and suppressing intestinal oxidative stress and injury in mice.
Nutritional and Functional Benefits
- Rosehips are rich in vitamins, minerals, and essential fatty acids, making them a valuable dietary supplement with various health-promoting properties.
- Different Rosa species exhibited varying levels of phenolic content and antioxidant capacity, with R. spinosissima showing the highest levels, indicating its potential as a reliable source of natural antioxidants.

Conclusion

Rosehips are generally safe for consumption and use in various therapeutic applications. They exhibit significant anti-inflammatory and antioxidant properties, making them beneficial for conditions like osteoarthritis and potentially useful in cancer therapy. Their rich nutritional profile further supports their use as a dietary supplement. Overall, rosehips present a promising natural remedy with a high safety margin and multiple health benefits.

Summary

Consensus Meter

Introduction

Key Insights

Conclusion

Sources and full results

A comparative study of efficacy and safety of glucosamine plus chondroitin sulphate versus rosehip as add on therapy to NSAIDs in patients suffering from osteoarthritis

Rosehip is significantly more effective than glucosamine and chondroitin sulphate as an add-on therapy for osteoarthritis patients, but both drugs are considered safe.

Efficacy and safety of a rosehip seed oil extract in the prevention and treatment of skin lesions in the hands of patients with type 1 diabetes mellitus caused by finger prick blood glucose monitoring; a randomized, open-label, controlled clinical trial

Rosehip seed oil is safe but not effective for improving skin lesions in the hands of patients with type 1 diabetes mellitus caused by finger prick blood glucose monitoring.

Evaluation of genotoxicity and subchronic toxicity of standardized rose hip extract

Standardized rose hip extract (RHPMJ) shows no genotoxicity and no observed adverse effects greater than 1000 mg/kg in rats after repeated oral dose toxicity studies.

Rosehip - an evidence based herbal medicine for inflammation and arthritis.

Standardised rosehip powder effectively reduces pain and inflammation in conditions like arthritis, with potential as a viable alternative to conventional therapies without ulcerogenic effects or platelet inhibition.

Bioactive Compounds and Antioxidant Activity in the Fruit of Rosehip (Rosa canina L. and Rosa rubiginosa L.)

Rosehip fruits, particularly those from Rosa rubiginosa L., contain high levels of bioactive compounds and antioxidant activity, potentially benefiting functional foods and disease prevention.

Beauty is as beauty does - culinary and medicinal use of rosehips

Rosehips are used in culinary and medicinal products due to their high levels of antioxidant compounds, vitamins, and unsaturated fatty acids, and their potential for treating osteoarthritis and stomach problems.

Effect of Rosehip (Rosa canina) Extracts on Human Brain Tumor Cell Proliferation and Apoptosis

Rosehip extracts effectively decrease glioblastoma cell proliferation without promoting apoptosis, potentially serving as an alternative or complement to current chemotherapeutic regimens for glioblastomas.

Antioxidative protection of dietary rosehips and polyphenol active lactobacilli in mice subjected to intestinal oxidative stress by ischemia-reperfusion

Lactobacillus strains combined with rosehips, especially R. pimpinellifolia, may prevent and suppress ischemia-reperfusion injury in the intestines by metabolizing polyphenols in rosehips.

Rosehip (Rosa canina) as a Beneficial Dietary Feed in Poultry Nutrition: Review

Rosehip (Rosa canina) at appropriate doses in poultry feed can provide beneficial effects, including increased vitamin C, minerals, and antioxidants.

Total Polyphenol Content and Antioxidant Capacity of Rosehips of Some Rosa Species

Rosehips from R. spinosissima have the highest phenolic and antioxidant content, making them a reliable source of natural antioxidants and suitable for plant breeding activities.

Try another search