Side effects of lisinopril hctz 20 12.5 mg
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Side Effects of Lisinopril HCTZ 20/12.5 mg
Common Side Effects of Lisinopril HCTZ
Lisinopril combined with hydrochlorothiazide (HCTZ) is commonly used to treat hypertension. However, like all medications, it can cause side effects. The most frequently reported side effects include cough, dizziness, and headache. Cough is particularly noted as a common adverse effect associated with lisinopril . Dizziness and headache are also frequently reported, likely due to the blood pressure-lowering effects of the medication .
Metabolic Side Effects
The combination of lisinopril and HCTZ can also lead to several metabolic changes. One significant effect is an increase in plasma uric acid levels, which can potentially lead to gout in susceptible individuals . Additionally, this combination can cause a decrease in potassium levels, which is a common side effect of hydrochlorothiazide . Conversely, lisinopril alone tends to increase potassium levels, so the combination may balance this effect to some extent.
Electrolyte Imbalances
Electrolyte imbalances are another concern with the use of lisinopril HCTZ. The combination can lead to decreased potassium levels, which can cause symptoms such as muscle weakness, cramps, and fatigue . Monitoring of electrolyte levels is recommended during treatment to prevent severe imbalances .
Cardiovascular Effects
While the primary purpose of lisinopril HCTZ is to manage hypertension, it can also have other cardiovascular effects. For instance, the combination has been shown to significantly reduce blood pressure, which can be beneficial but may also lead to hypotension in some patients . Additionally, heart rate may decrease slightly with this combination therapy.
Rare but Serious Side Effects
Though rare, some serious side effects have been reported. These include angioedema, a severe allergic reaction that can cause swelling of the face, lips, tongue, or throat, and can be life-threatening if not treated promptly. Another rare but serious side effect is proteinuria, which is the presence of excess proteins in the urine and can indicate kidney damage.
Conclusion
Lisinopril HCTZ 20/12.5 mg is effective in managing hypertension but comes with a range of potential side effects. Common side effects include cough, dizziness, and headache, while metabolic changes such as increased uric acid and decreased potassium levels are also notable. Electrolyte imbalances and cardiovascular effects should be monitored, and rare but serious side effects like angioedema and proteinuria require immediate medical attention. Regular monitoring and consultation with a healthcare provider can help manage these risks effectively.
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