Side effects of xanax
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Side Effects of Xanax (Alprazolam)
Central Nervous System Depression
One of the primary side effects of Xanax (alprazolam) is central nervous system (CNS) depression. This effect can interfere with normal physiological functions, such as nocturnal acid clearance mechanisms. In a study involving healthy volunteers, it was found that alprazolam significantly decreased upper esophageal sphincter pressure and led to abnormal amounts of nocturnal acid reflux in one-third of the participants. This suggests that CNS depression induced by alprazolam can disrupt normal esophageal function and acid reflux management during sleep.
Drowsiness and Sedation
Drowsiness is one of the most frequently reported side effects of alprazolam. In a clinical trial assessing the efficacy of alprazolam in treating moderate to severe anxiety, drowsiness was the most common side effect reported by patients. Despite its effectiveness in reducing anxiety, the sedative properties of alprazolam can significantly impact daily functioning and alertness.
Mild and Transient Adverse Effects in Children
In a study involving children with anxiety disorders, alprazolam was generally well-tolerated, with adverse effects being infrequent, mild, and transient. The study reported no clinically significant changes in laboratory values, blood pressure, pulse, or respiration during the four weeks of alprazolam administration. However, a significant increase in body weight was observed, with a mean increase of 0.87 kg. This suggests that while alprazolam can be effective in managing anxiety in children, it may also lead to weight gain and other mild side effects.
Conclusion
Xanax (alprazolam) is an effective anxiolytic agent with several side effects. Central nervous system depression can lead to issues such as nocturnal acid reflux, while drowsiness is a common side effect that can affect daily activities. In children, alprazolam is generally well-tolerated, though it may cause mild and transient adverse effects, including weight gain. These findings highlight the importance of monitoring and managing side effects when using alprazolam for anxiety treatment.
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