Signs & symptoms of breast cancer
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Summary
10 papers analyzed
These studies suggest that common signs and symptoms of breast cancer include fatigue, cognitive impairment, mood problems, psychological symptoms, and lymphedema, with variations across treatment stages and patient demographics.
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Signs and Symptoms of Breast Cancer
Common Symptom Clusters in Breast Cancer Patients
Breast cancer patients often experience a range of symptoms that can significantly impact their quality of life. These symptoms frequently cluster together, sharing common underlying causes. The most commonly reported symptom clusters include fatigue, sleep disturbances, and psychological symptoms such as anxiety, depression, nervousness, irritability, sadness, and worry . These clusters can vary across different stages of cancer treatment, highlighting the need for tailored symptom management strategies .
Symptoms Across Different Phases of Breast Cancer
Early-Stage Breast Cancer
In early-stage breast cancer, symptoms often include fatigue, perceived cognitive impairment, and mood problems. Pain is a less common presenting symptom, with only 5% of patients reporting it initially, although 33% admit to experiencing pain upon further questioning. Other symptoms in early stages can include skin tethering or fixation, nipple retraction or displacement, and well-defined lesions.
Metastatic Breast Cancer
Patients with metastatic breast cancer report more severe symptoms, including general pain, nausea, decreased appetite, and diarrhea. These symptoms are often more intense and persistent compared to those in early-stage patients, necessitating more aggressive symptom management.
Inflammatory Breast Cancer (IBC)
Inflammatory breast cancer (IBC) is a rare but aggressive form of breast cancer that presents with distinct symptoms such as erythema, skin changes like peau d'orange, nipple inversion, edema, and warmth of the affected breast. These symptoms can be easily mistaken for benign conditions like mastitis, leading to delays in diagnosis and treatment.
Lymphedema in Breast Cancer Survivors
Lymphedema, characterized by swelling in the breast, axilla, arm, or hand, is a common side effect of breast cancer treatment. It is more prevalent among African American women and those with low income. Symptoms include tissue fibrosis, pitting, hemosiderin staining, and a feeling of heaviness. Despite its prevalence, lymphedema is often underdiagnosed, particularly in minority and low-income groups.
Patient-Reported Outcomes and Symptom Burden
Patient-reported outcomes (PROs) highlight the significant symptom burden experienced by breast cancer patients. Commonly reported symptoms include anxiety, decreased appetite, fatigue, general pain, mouth sores, muscle pain, nausea, vomiting, numbness, sadness, shortness of breath, diarrhea, constipation, and insomnia. These symptoms can vary in severity and frequency, with some patients experiencing moderate to severe symptoms throughout their treatment.
Conclusion
Understanding the signs and symptoms of breast cancer is crucial for timely diagnosis and effective management. Symptom clusters such as fatigue, psychological distress, and pain are common across different stages of the disease. Special attention should be given to aggressive forms like IBC and conditions like lymphedema, which are often underdiagnosed. Tailored symptom management strategies based on patient-reported outcomes can significantly improve the quality of life for breast cancer patients.
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