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These studies suggest that basal cell carcinoma (BCC) is a common, slow-growing skin cancer with various subtypes and treatment options, including surgery as the standard approach, photodynamic therapy for nonaggressive forms, and advanced treatments like hedgehog pathway inhibitors for complex cases.
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Basal cell carcinoma (BCC) is the most common form of skin cancer, predominantly affecting fair-skinned individuals and those with significant sun exposure . It originates from the basal cells in the epidermis and is characterized by its slow growth and low likelihood of metastasis . Despite its low mortality rate, BCC can cause significant morbidity due to local tissue invasion and potential disfigurement .
Nodular BCC is the most prevalent subtype and typically presents as a pearly or waxy bump on the skin, often with visible blood vessels . These nodules can be flesh-colored, pink, or red and may develop a central depression or ulceration over time . The lesions are most commonly found on sun-exposed areas such as the face, neck, and ears .
Superficial BCC often appears as a flat, scaly, and reddish patch on the skin, which may resemble eczema or psoriasis . These patches are usually found on the trunk and limbs and can be multiple, making them easily mistaken for benign skin conditions .
Infiltrative BCC is less common but more aggressive. It presents as a scar-like lesion that is firm to the touch and may be slightly raised or flat. These lesions can be more challenging to diagnose due to their subtle appearance and tendency to blend with the surrounding skin.
Mixed BCC exhibits characteristics of both nodular and infiltrative types, making it more complex to identify and treat. These lesions can present with a combination of nodular bumps and scar-like areas, often requiring a biopsy for accurate diagnosis.
BCC lesions, particularly nodular and infiltrative types, can ulcerate and bleed easily, especially when traumatized . This symptom is a key indicator that differentiates BCC from other benign skin conditions.
Some patients may experience itching or discomfort in the area of the BCC lesion, although this is not as common as other symptoms . Persistent itching in a localized area should prompt further investigation.
A significant issue with BCC is the delay in presentation, often due to denial or misinterpretation of symptoms as benign. Early recognition and treatment are crucial to prevent extensive tissue involvement and improve cosmetic and functional outcomes.
Basal cell carcinoma presents with a variety of symptoms depending on its subtype, ranging from pearly nodules to flat, scaly patches and scar-like lesions. Early detection and treatment are essential to minimize morbidity and achieve better cosmetic results. Awareness of the common symptoms and prompt medical consultation can significantly improve patient outcomes.
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