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These studies suggest that stage 1 hypertension increases the risk of cardiovascular disease, poor pregnancy outcomes, and adverse events across various demographics, emphasizing the need for effective control and tailored prevention strategies.
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Hypertension, commonly known as high blood pressure, is a significant risk factor for cardiovascular diseases (CVD) and other health complications. The 2017 American College of Cardiology/American Heart Association (ACC/AHA) guidelines redefined the thresholds for hypertension, categorizing it into different stages based on systolic and diastolic blood pressure (BP) readings. This article explores the stages of hypertension, their associated risks, and the importance of early detection and management.
Stage 1 hypertension is defined by the ACC/AHA guidelines as having a systolic BP between 130-139 mm Hg or a diastolic BP between 80-89 mm Hg . This redefinition has brought attention to the need for early intervention to prevent the progression to more severe stages of hypertension and associated health risks.
Research indicates that stage 1 hypertension significantly increases the risk of cardiovascular events. A meta-analysis found that individuals with stage 1 hypertension have a 38% higher risk of cardiovascular disease (CVD) events compared to those with normal BP. This includes increased risks for coronary heart disease (CHD), stroke, CVD morbidity, and CVD mortality . Specifically, the hazard ratios for CHD, stroke, CVD morbidity, and CVD mortality were 1.30, 1.39, 1.42, and 1.34, respectively.
Young adults with stage 1 hypertension are also at increased risk for adverse cardiovascular outcomes. Studies from the CARDIA cohort and the Kailuan Study have shown that young adults with stage 1 hypertension have higher rates of CVD events, including coronary heart disease, stroke, and heart failure, compared to those with normal BP. The hazard ratios for CVD events in young adults with stage 1 hypertension were found to be 1.75 and 1.82 in different studies.
Stage 2 hypertension is defined as having a systolic BP of 140 mm Hg or higher or a diastolic BP of 90 mm Hg or higher . This stage represents a more severe level of hypertension and is associated with a higher risk of cardiovascular complications.
Longitudinal studies have shown that a significant proportion of individuals with stage 1 hypertension progress to stage 2 hypertension over time. For instance, a Korean cohort study found that 52.8% of participants developed stage 1 hypertension, and 23.6% progressed to stage 2 hypertension over a median follow-up period of 12.23 years. The progression from normal BP to stage 2 hypertension took an average of 8.7 years for those following a typical progression path.
Stage 1 hypertension in pregnant women has been associated with poor neonatal outcomes. A meta-analysis revealed that stage 1 hypertension increases the risk of preterm delivery, small for gestational age, low birth weight, and early-term delivery. These findings highlight the importance of monitoring and managing BP in pregnant women to prevent adverse outcomes.
In sub-Saharan Africa, the prevalence of stage 1 hypertension is high, with over 25% of the population affected in many countries. Despite the high prevalence, rates of diagnosis, treatment, and control are markedly low, emphasizing the need for improved healthcare strategies and interventions in this region.
Hypertension, particularly stage 1 hypertension, poses significant health risks and can lead to severe cardiovascular events if not managed effectively. Early detection and appropriate management, including lifestyle modifications and, in some cases, medication, are crucial in preventing the progression to more severe stages of hypertension and reducing the associated health risks. Public health strategies should focus on increasing awareness, improving screening, and providing effective treatment options to manage hypertension and mitigate its impact on global health.
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