Atrial fibrillation is associated with more severe hypoperfusion, infarct growth, and hemorrhagic transformation in ischemic stroke patients, leading to worse functional outcomes.

Worse Stroke Outcome in Atrial Fibrillation is Explained by More Severe Hypoperfusion, Infarct Growth, and Hemorrhagic Transformation

Noninvasive ambulatory ECG monitoring for 30 days significantly improved detection of atrial fibrillation and nearly doubled the rate of anticoagulant treatment in patients with cryptogenic stroke or TIA.

Atrial fibrillation in patients with cryptogenic stroke.

Oral anticoagulation benefits stroke prevention in atrial fibrillation patients, outweighing the risk of bleeding from falls.

Balancing the risk of stroke and bleeding in atrial fibrillation patients with a history of falls

Atrial fibrillation may be newly detected in nearly a quarter of patients with stroke or transient ischaemic attack, potentially increasing the number of patients treated with oral anticoagulants and preventing stroke recurrence.

Diagnosis of atrial fibrillation after stroke and transient ischaemic attack: a systematic review and meta-analysis

Antithrombotic therapy is effective and safe for preventing stroke in patients with atrial fibrillation, as demonstrated by a meta-analysis of randomized clinical trials.

Antithrombotic Therapy To Prevent Stroke in Patients with Atrial Fibrillation

High-quality epidemiologic studies are needed to better understand the worldwide burden of atrial fibrillation and stroke in AF, and major improvements in thromboprophylaxis are needed in many countries.

The Global Burden of Atrial Fibrillation and Stroke: A Systematic Review of the Clinical Epidemiology of Atrial Fibrillation in Asia

Atrial fibrillation is a strong risk factor for stroke, and early screening and treatment with direct oral anticoagulants can effectively mitigate the risk of future strokes.

Stroke in Patients with Atrial Fibrillation: Epidemiology, Screening, and Prognosis

Oral anticoagulation reduces ischemic stroke risk in atrial fibrillation patients, but increases systemic bleeding risk.

Management and Prognosis of Acute Stroke in Atrial Fibrillation

Stroke prevention in atrial fibrillation patients is crucial, and non-vitamin K antagonist oral anticoagulants are recommended over warfarin for optimal outcomes.

Stroke Prevention in Atrial Fibrillation

Apixaban reduces stroke risk in patients with subclinical atrial fibrillation but increases major bleeding risk compared to aspirin.

Apixaban for Stroke Prevention in Subclinical Atrial Fibrillation.

Anticoagulation therapy reduces stroke risk by 62% in atrial fibrillation patients, with greater benefits for high-risk patients and those with risk factors like age, hypertension, and diabetes.

Comparing the guidelines: anticoagulation therapy to optimize stroke prevention in patients with atrial fibrillation.

Emergency department patients with infection and new-onset atrial fibrillation without current oral anticoagulant therapy have a 2.7% absolute one-year risk of stroke, mainly related to sex, age, and risk factors identified by the CHA2DS2-VASc score.

New-onset atrial fibrillation among patients with infection in the emergency department: A multicentre cohort study of one-year stroke risk.

Subclinical atrial tachyarrhythmias, detected by pacemakers, are frequently found in patients with no history of atrial fibrillation and are associated with a significantly increased risk of ischemic stroke or systemic embolism.

Subclinical atrial fibrillation and the risk of stroke.

Anticoagulant therapy for non-valvular atrial fibrillation is often not used according to stroke risk scores and guidelines, with overuse in low-risk patients and underuse in those at high risk of stroke.

Risk Profiles and Antithrombotic Treatment of Patients Newly Diagnosed with Atrial Fibrillation at Risk of Stroke: Perspectives from the International, Observational, Prospective GARFIELD Registry

Atrial fibrillation (AF) is associated with a five-fold increased risk of stroke, and an integrated care approach is essential for effective management and prevention of both conditions.

Atrial fibrillation and stroke

Female patients with atrial fibrillation have a higher risk of stroke compared to men, with a significant relationship between age and stroke risk in women.

Sex differences in stroke and major adverse clinical events in patients with atrial fibrillation: A systematic review and meta-analysis of 993,600 patients.

New post-operative atrial fibrillation after noncardiac surgery increases the risk of stroke by 2.5-fold, with higher risk in patients undergoing non-thoracic noncardiac surgery.

Post-operative Atrial Fibrillation following Noncardiac Surgery Increases Risk of Stroke.

Pattern of atrial fibrillation strongly predicts stroke risk in non-anticoagulated patients, aiding in assessing the risk/benefit of anticoagulant therapy.

Risk of ischaemic stroke according to pattern of atrial fibrillation: analysis of 6563 aspirin-treated patients in ACTIVE-A and AVERROES.

Oral-anticoagulation therapy is crucial for managing atrial fibrillation in older people, but misconceptions about bleeding risk may prevent its use due to age-related factors.

Atrial Fibrillation in Older People: Concepts and Controversies

Atrial fibrillation does not affect the treatment effect of endovascular thrombectomy for acute ischemic stroke patients with large vessel occlusion, and there is no difference in outcomes between those with and without atrial fibrillation.

Effect of atrial fibrillation on endovascular thrombectomy for acute ischemic stroke. A meta-analysis of individual patient data from six randomised trials: Results from the HERMES collaboration

Stroke in Patients with Atrial Fibrillation

These studies suggest that atrial fibrillation significantly increases stroke risk and severity, but early detection and treatment with oral anticoagulants can effectively reduce this risk despite an increased bleeding risk.