Sunlight antibiotics
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The Impact of Sunlight on Antibiotics: Efficacy and Degradation
Introduction to Sunlight and Antibiotics
Sunlight plays a significant role in the degradation and efficacy of antibiotics in various environments, including agriculture, wastewater treatment, and natural water bodies. Understanding how sunlight affects antibiotics is crucial for managing their use and mitigating the spread of antibiotic resistance.
Sunlight's Effect on Agricultural Antibiotics
Oxytetracycline and Streptomycin in Agriculture
In agricultural settings, antibiotics like oxytetracycline and streptomycin are commonly used to treat diseases such as citrus greening disease (CGD). However, sunlight exposure significantly impacts their efficacy. Studies have shown that oxytetracycline's antibiotic potential dramatically decreases after 14 days of sunlight exposure, affecting both Gram-negative (Escherichia coli) and Gram-positive (Bacillus subtilis) bacteria. In contrast, streptomycin's effectiveness is only moderately impacted by sunlight over the same period .
Sunlight in Wastewater Treatment
UV-C/H2O2 and Sunlight/H2O2 Processes
In urban wastewater treatment, sunlight combined with hydrogen peroxide (H2O2) has been explored for removing antibiotics like ciprofloxacin and sulfamethoxazole. While UV-C/H2O2 processes can fully remove these antibiotics, sunlight/H2O2 is less effective, particularly for sulfamethoxazole. Despite this, both processes can inactivate antibiotic-resistant bacteria (ARB) such as E. coli and Pseudomonas aeruginosa, although regrowth can occur after treatment.
Solar Photo-Fenton Process
The solar photo-Fenton process, which uses solar light and iron catalysts, has proven effective in disinfecting water from ARB and reducing antibiotic resistance genes (ARGs). This method ensures that both antibiotic-susceptible and resistant strains are eliminated, preventing the spread of resistance in the environment.
Photocatalytic Degradation of Antibiotics
CdS/BiOBr Heterojunction Photocatalyst
Innovative photocatalysts like the CdS/BiOBr heterojunction have shown high performance in degrading antibiotics such as ciprofloxacin and norfloxacin under natural sunlight. This heterojunction enhances photocatalytic activity by reducing charge carrier recombination and increasing visible light absorption, leading to complete degradation of the antibiotics.
TiO2/Nitrogen-Doped Holey Graphene Nanocomposite
Another promising photocatalyst is the TiO2/nitrogen-doped holey graphene (TiO2/NHG) nanocomposite, which effectively degrades cefixime under sunlight. This method offers good scalability and highlights the potential of nanotechnology in wastewater treatment.
Perylene Diimide Supramolecular Nanofibers
Perylene diimide (PDI) supramolecular nanofibers have also been identified as effective sunlight-driven photocatalysts for treating fluoroquinolone antibiotics, including ofloxacin. These nanofibers achieve rapid degradation through mechanisms involving reactive species like hydroxyl radicals and superoxide anions.
Photolysis and Photocatalysis in Water
General Photodegradation Mechanisms
Sunlight-induced photolysis and photocatalysis are crucial for degrading antibiotics in water. These processes involve direct and mediated actions of sunlight, leading to the formation of various phototransformation products. For instance, TiO2-photocatalysis has been widely studied for its ability to eliminate antibiotics from water.
Enhanced Photocatalytic Activity with N,S-Doped Carbon Quantum Dots
Functionalized N,S-doped carbon quantum dots embedded in ZnO nanoflowers have shown enhanced photocatalytic activity under sunlight. This hybrid nanoflower can degrade a significant percentage of antibiotics like ciprofloxacin, making it a promising solution for industrial applications.
Conclusion
Sunlight significantly impacts the efficacy and degradation of antibiotics in various environments. While it can reduce the effectiveness of certain antibiotics in agriculture, it also offers potential solutions for wastewater treatment through advanced photocatalytic processes. Understanding these interactions is essential for developing strategies to manage antibiotic use and combat antibiotic resistance.
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