Symptoms lactic acid build up
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Symptoms of Lactic Acid Build-Up
Lactic acid build-up, also known as lactic acidosis, can present with a variety of symptoms that are often related to the underlying cause of the condition. This article synthesizes findings from multiple research studies to provide a comprehensive overview of the symptoms associated with lactic acid build-up.
Common Symptoms of Lactic Acidosis
Kussmaul Breathing
One of the hallmark symptoms of lactic acidosis is Kussmaul breathing, which is characterized by deep and labored breathing. This type of breathing is a compensatory mechanism to counteract the metabolic acidosis by expelling more carbon dioxide from the body.
Neurological Symptoms: Confusion and Slurred Speech
Patients with lactic acidosis often exhibit neurological symptoms such as confusion and slurred speech. These symptoms are indicative of the brain's response to the altered metabolic state and the accumulation of lactic acid in the bloodstream.
Gait Disturbances
Gait disturbances, including difficulty walking or maintaining balance, are also commonly reported in individuals experiencing lactic acidosis. This symptom further underscores the impact of lactic acid build-up on the nervous system.
Gastrointestinal Symptoms: Vomiting and Diarrhea
Lactic acid build-up can also lead to gastrointestinal symptoms such as vomiting and diarrhea. These symptoms are often seen in cases where lactic acid bacteria (LAB) produce biogenic amines in fermented foods, leading to toxic effects.
Cardiovascular Symptoms: Heart Palpitations
Heart palpitations are another symptom associated with lactic acid build-up. This can occur due to the toxic effects of biogenic amines produced by LAB, which can affect cardiovascular function.
Specific Conditions Leading to Lactic Acidosis
Short Bowel Syndrome
Lactic acidosis is particularly common in individuals with short bowel syndrome, a condition where a significant portion of the small intestine is missing or non-functional. In these patients, symptoms such as Kussmaul breathing, confusion, slurred speech, and gait disturbances are frequently observed.
Diabetes Mellitus
In diabetic patients, lactic acidosis can occur due to the accumulation of both ketone bodies and D-lactic acid. This dual accumulation can exacerbate the symptoms and complicate the clinical picture.
Propylene Glycol Intoxication
High levels of D-lactic acid have also been documented in cases of propylene glycol intoxication. This condition can lead to similar symptoms of lactic acidosis, including neurological and gastrointestinal disturbances.
Conclusion
Lactic acid build-up can manifest through a range of symptoms, including Kussmaul breathing, confusion, slurred speech, gait disturbances, vomiting, diarrhea, and heart palpitations. These symptoms can vary depending on the underlying cause, such as short bowel syndrome, diabetes mellitus, or propylene glycol intoxication. Understanding these symptoms is crucial for the timely diagnosis and management of lactic acidosis.
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