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These studies suggest that tip of the tongue numbness can be caused by central neurological issues, surgical manipulations, or nerve damage from medical procedures.
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Thalamic Hemorrhage and Sensory Disturbance
Numbness in the tip of the tongue can be a rare manifestation of a thalamic stroke. Specifically, a hemorrhage in the thalamic ventroposteromedial (VPM) nucleus can lead to severe numbness in the tongue and lower lip. This is due to the disruption of the somatosensory pathways that convey sensory information from the tongue via the lingual nerve to the contralateral medial VPM proper. The complexity of the vascular supply in this region means that small-vessel disease can present with diverse symptoms, including isolated numbness in the tongue and lip.
Hemispheric Stroke and Isolated Tongue Numbness
Similarly, isolated numbness at the tip of the tongue can also result from a hemispheric stroke. In one case, a hypertensive woman experienced acute onset numbness at the tip of her tongue due to small infarctions in the postcentral gyrus of the right parietal lobe. This highlights the importance of considering central neurological involvement in cases of sensory disturbances at the tongue tip.
Post-Surgical Lingual Nerve Injury
Lingual nerve injury is another common cause of tongue numbness, often occurring after surgical procedures. For instance, the use of laryngeal mask airways during surgeries has been associated with transient lingual nerve injury, leading to numbness at the tongue tip. Fortunately, such cases typically resolve spontaneously within a few weeks. Additionally, dental procedures involving lingual nerve injections can result in prolonged paresthesia of the tongue, significantly affecting the patient's quality of life.
Anatomical Considerations in Surgical Procedures
The course and distribution of the lingual nerve in the ventral tongue region are crucial for understanding potential injury during surgical procedures. Detailed anatomical studies have shown that the lingual nerve innervates the tongue tip and can be damaged during manipulations in this area, leading to numbness. This knowledge is essential for performing safe surgical procedures like frenectomy.
Pathogenesis and Symptoms
Neck-tongue syndrome is characterized by simultaneous suboccipital pain and ipsilateral numbness of the tongue, often triggered by sudden head movements. This condition is thought to result from the compression of the second cervical root in the atlantoaxial space, affecting afferent fibers from the lingual nerve . Familial cases suggest a possible autosomal dominant inheritance pattern.
Chorda Tympani Nerve Involvement
Patients undergoing middle ear surgery often report numbness of the tongue, which may or may not be accompanied by taste alterations. Studies have shown that the chorda tympani nerve, which is involved in taste sensation, also contributes to the general sensory function of the tongue. Post-operative numbness correlates with objective reductions in sensory sensitivity, which typically return to baseline over time.
Numbness at the tip of the tongue can arise from various causes, including thalamic and hemispheric strokes, lingual nerve injuries during surgical procedures, neck-tongue syndrome, and otologic surgeries. Understanding the underlying mechanisms and anatomical considerations is crucial for accurate diagnosis and effective management of this sensory disturbance.
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