What does cancer remission mean
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Summary
10 papers analyzed
These studies suggest that cancer remission refers to a state where cancer symptoms are reduced or disappear, which can occur spontaneously but is rare and may involve various mechanisms such as immune response, surgery, or treatment.
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Understanding Cancer Remission: Definitions and Implications
What is Cancer Remission?
Cancer remission refers to a state where the signs and symptoms of cancer are reduced or disappear. This can be either partial or complete. In partial remission, some, but not all, signs and symptoms of cancer have disappeared. In complete remission, all signs and symptoms of cancer are gone, although this does not necessarily mean the cancer has been cured .
Types of Remission
Spontaneous Remission
Spontaneous remission is a rare phenomenon where cancer regresses without any medical treatment or with treatment that is considered inadequate to produce such a result. This can occur in various types of cancer, including lung cancer, leukemia, and uterine cervix cancer . The exact mechanisms behind spontaneous remission are not well understood, but factors such as immune response, hormonal changes, and elimination of carcinogens are thought to play a role .
Induced Remission
Induced remission occurs as a result of medical treatment, such as chemotherapy, radiation, or surgery. This type of remission is more common and is often the goal of cancer treatment plans. For instance, in non-small cell lung cancer (NSCLC), long-term survival and remission have been achieved through multiple lines of chemotherapy combined with radiation or surgery.
Psychological and Social Aspects of Remission
Cancer remission is not just a medical milestone but also a significant psychological and social event. Patients in remission often experience a mix of emotions, including relief, anxiety about recurrence, and a renewed appreciation for life. The sense of coherence and meaning in life can significantly impact the quality of life for cancer survivors in remission . Studies have shown that factors such as a strong sense of responsibility and consistency in life goals are dominant in patients experiencing remission.
Clinical Features and Prognosis
The prognosis for patients in remission can vary widely. In cases of spontaneous remission, the long-term outlook is often uncertain due to the unpredictable nature of the phenomenon. However, in induced remission, factors such as the stage of cancer at diagnosis, the type of treatment received, and the patient's overall health play crucial roles in determining the prognosis. For example, in advanced NSCLC, patients who achieved complete remission often had smaller primary tumors and fewer metastases, and their treatment included aggressive management of both primary and metastatic sites.
Conclusion
Cancer remission, whether spontaneous or induced, represents a complex interplay of medical, psychological, and social factors. While spontaneous remission remains a rare and poorly understood event, induced remission through targeted treatments offers a more predictable path to managing cancer. Understanding the nuances of remission can help healthcare providers improve communication and care planning, ultimately enhancing the quality of life for cancer survivors.
Sources and full results
Most relevant research papers on this topic
4
[Spontaneous tumor regression].
4
28 Citations
1998
8
[Spontaneous remission in cancer].
8
6 Citations
2004