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10 papers analyzed
Some studies suggest that long-term NSAID use effectively reduces pain and inflammation, while other studies highlight significant risks including gastrointestinal, cardiovascular, renal, and other serious side effects, especially in elderly patients and those with comorbidities.
20 papers analyzed
Non-steroidal anti-inflammatory drugs (NSAIDs) are widely used for their analgesic and anti-inflammatory properties, particularly in conditions such as osteoarthritis, rheumatoid arthritis, and chronic pain. However, the long-term use of NSAIDs is associated with various adverse effects, which necessitates a careful evaluation of their benefits and risks.
Pain Management and Efficacy
Gastrointestinal Risks
Renal Risks
Cardiovascular Risks
Alternative Approaches
Opioid Use and Cancer
Long-term use of NSAIDs provides short-term pain relief but is associated with significant risks, including gastrointestinal, renal, and cardiovascular complications. These risks necessitate careful consideration and often the adoption of alternative pain management strategies to minimize adverse effects. While NSAIDs can reduce opioid dependency in certain conditions like cancer, their overall long-term benefits remain limited, and their use should be carefully monitored, especially in high-risk populations.
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