10 papers analyzed
These studies suggest that epigenetic processes, including DNA methylation, histone modification, and RNA-mediated processes, play a crucial role in regulating gene expression, affecting development, disease, and potential therapies.
Epigenetics refers to heritable changes in gene expression that do not involve alterations to the underlying DNA sequence. These changes are crucial for various biological processes, including development, differentiation, and disease manifestation. Epigenetic mechanisms such as DNA methylation, histone modification, and RNA-mediated processes play significant roles in regulating gene expression.
DNA Methylation and Gene Expression:
Histone Modifications:
RNA-Mediated Processes:
Chromatin Structure and Gene Regulation:
Environmental Influences:
Epigenetic Variability and Disease:
Transgenerational Epigenetic Inheritance:
Epigenetic mechanisms, including DNA methylation, histone modifications, and RNA-mediated processes, play crucial roles in regulating gene expression. These processes are influenced by environmental factors and can lead to significant variability in gene expression, impacting development, differentiation, and disease. Understanding these mechanisms offers potential for novel therapeutic approaches in treating various diseases.
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