Reducing saturated fatty acid intake in children significantly reduces total and LDL-cholesterol levels and diastolic blood pressure without adverse effects on growth and development.

Health effects of saturated and trans-fatty acid intake in children and adolescents: Systematic review and meta-analysis

Saturated fat intake is not consistently associated with increased risk of all cause mortality, CVD, CHD, ischemic stroke, or type 2 diabetes, while trans fat intake is associated with increased risk of all cause mortality, CHD, and type 2 diabetes.

Intake of saturated and trans unsaturated fatty acids and risk of all cause mortality, cardiovascular disease, and type 2 diabetes: systematic review and meta-analysis of observational studies

Dietary saturated fat is not significantly associated with an increased risk of coronary heart disease, stroke, or cardiovascular disease.

Meta-analysis of prospective cohort studies evaluating the association of saturated fat with cardiovascular disease.

High saturated fat diets may increase the risk of diabetes and cardiovascular disease, but Mediterranean diets with healthy monounsaturated fats may be more effective in preventing these diseases.

Cardio-Metabolic Effects of High-Fat Diets and Their Underlying Mechanisms—A Narrative Review

Reducing saturated fatty acid intake does not significantly reduce cardiovascular disease risk or total mortality, and may even protect against stroke.

Saturated Fats and Health: A Reassessment and Proposal for Food-based Recommendations: JACC State-of -the-Art Review.

The health effects of saturated fats on cardiovascular health are complex and dependent on the presence of other nutrients and the associated dietary pattern.

The health effects of saturated fats - the role of whole foods and dietary patterns.

Dietary fat intake has a significant impact on mortality rates, with higher intake of polyunsaturated fat reducing all-cause and cardiovascular disease mortality, while high intake of saturated fat increases all-cause and cancer mortality.

Association between dietary fat intake and mortality from all-causes, cardiovascular disease, and cancer: A systematic review and meta-analysis of prospective cohort studies.

A single oral saturated fat load rapidly increases hepatic lipid storage, energy metabolism, and insulin resistance, potentially contributing to the development of nonalcoholic fatty liver disease.

Acute dietary fat intake initiates alterations in energy metabolism and insulin resistance

Consumption of trans-fatty acids from partially hydrogenated oils significantly increases the risk of coronary heart disease events, with more limited public health implications for ruminant TFA.

Health effects of trans-fatty acids: experimental and observational evidence

Reducing saturated fat intake reduces the risk of cardiovascular events by 17%, but has little or no effect on all-cause mortality.

Reduction in saturated fat intake for cardiovascular disease.

Replacing saturated fat with PUFA, MUFA, or high-quality carbohydrates can lower CHD events and CVD mortality, while replacing it with carbohydrate does not.

A systematic review of the effect of dietary saturated and polyunsaturated fat on heart disease.

Limiting saturated fat intake may not be as strong as previously thought, with inconsistent results in randomized controlled trials.

Dietary saturated fat and heart disease: a narrative review.

Dietary saturated fat is not the villain we once thought it was, and overall diet quality and eliminating processed foods, including simple carbohydrates, may be more beneficial for cardiovascular disease and overall health.

Saturated Fat: Part of a Healthy Diet

Dietary saturated fats, particularly in dairy products and coconut oil, may improve health and may not increase the risk of coronary artery disease, while 6 polyunsaturated fatty acids may promote inflammation and contribute to various diseases.

Dietary fats and health: dietary recommendations in the context of scientific evidence.

Substituting 9.5-9.6% of dietary saturated fats with monounsaturated fatty acids or n-6 polyunsaturated fatty acids has beneficial effects on serum lipid biomarkers, blood pressure, and E-selectin, but not on vascular function.

Replacement of saturated with unsaturated fats had no impact on vascular function but beneficial effects on lipid biomarkers, E-selectin, and blood pressure: results from the randomized, controlled Dietary Intervention and VAScular function (DIVAS) study.

Higher intakes of dairy-derived saturated fats are associated with a less atherogenic profile in males, while nondairy saturated fats show no significant adverse effects on these cardiometabolic outcomes.

Saturated fat from dairy sources is associated with lower cardiometabolic risk in the Framingham Offspring Study.

The U.S. Dietary Guidelines for Americans, which recommend limiting saturated fats to 10% of total energy intake, are based on insufficient and inconsistent evidence, and fail to consider the impact of food matrix and overall dietary patterns.

Dietary Saturated Fats and Health: Are the U.S. Guidelines Evidence-Based?

Replacing saturated fats with unsaturated fats significantly reduces cardiovascular disease risk, while trans fat intake increases it.

Dietary Fat and Risk of Cardiovascular Disease: Recent Controversies and Advances.

High-fat diets may promote intestinal inflammation, but certain saturated fats, like lauric and myristic fatty acid-rich coconut oil, may have anti-inflammatory and protective effects.

Regulation of Intestinal Inflammation by Dietary Fats

Elevated saturated fat consumption in the diet may not increase cardiovascular risk or all-cause mortality, as it may have a limited and restricted effect in the overall diet.

The PURE study and the enigmatic aspects of the diet: is it possible that an high saturated fat consumption would not be harmful?

What are the implications of recent research on the health effects of saturated fats?

Some studies suggest reducing saturated fat intake lowers cholesterol and blood pressure in children and reduces cardiovascular events, while other studies indicate no consistent association with increased risk of mortality or cardiovascular diseases, and emphasize the complexity of its health effects depending on overall diet.