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These studies suggest that stroke is defined by clinical and tissue criteria involving central nervous system infarction and intracerebral hemorrhage, with ischemic strokes being the most common type.
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Stroke is a medical condition characterized by the sudden onset of symptoms due to a disruption in the blood supply to the brain, leading to neurological deficits. Traditionally, stroke has been defined by the abrupt appearance of focal neurological dysfunction lasting more than 24 hours or resulting in death, caused by acute vascular injury to the brain . This definition encompasses both ischemic strokes, caused by inadequate blood supply, and hemorrhagic strokes, resulting from bleeding within the brain .
The American Heart Association/American Stroke Association has updated the definition of stroke to include both clinical and tissue criteria. Central nervous system infarction, which includes brain, spinal cord, or retinal cell death due to ischemia, is now a key component of the definition. This updated definition also recognizes silent infarctions, which do not present with overt symptoms, and includes intracerebral and subarachnoid hemorrhages.
Ischemic stroke, the most common type, occurs when a blood clot obstructs a blood vessel supplying the brain. This can result from small vessel arteriolosclerosis, cardioembolism, or large artery athero-thromboembolism. In younger patients, ischemic strokes can also be caused by extracranial dissection.
Hemorrhagic stroke, accounting for about 20% of all strokes, occurs when a blood vessel in the brain ruptures, leading to bleeding within the brain tissue. This can be due to deep perforator arteriopathy, cerebral amyloid angiopathy, or macrovascular lesions such as aneurysms and vascular malformations .
The absence of a definitive diagnostic test for stroke necessitates rapid and accurate clinical diagnosis to initiate emergency interventions. These interventions can restore brain perfusion, improve survival rates, and minimize the risk of early recurrent strokes.
Recent advancements in stroke treatment include endovascular thrombectomy for acute ischemic stroke, which significantly improves functional independence. Additionally, the use of direct oral anticoagulants for atrial fibrillation and carotid stenting for symptomatic carotid stenosis are notable strategies for preventing recurrent strokes.
Stroke is a complex cerebrovascular disorder with significant implications for health and mortality. The updated definition of stroke by leading health organizations incorporates both clinical symptoms and tissue damage, reflecting advances in medical science and technology. Understanding the types of stroke and the importance of rapid diagnosis and treatment is crucial for improving patient outcomes and reducing the global burden of this condition.
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