Ketogenic diets may provide short-term improvements for some chronic diseases, but their risks may outweigh the benefits for most individuals due to unfavorable dietary intake and inadequate long-term safety data.

Ketogenic Diets and Chronic Disease: Weighing the Benefits Against the Risks

A ketogenic diet effectively improves metabolic parameters, particularly glycemic control, weight reduction, and lipid profiles, in overweight or obese patients compared to low-fat diets.

Impact of a Ketogenic Diet on Metabolic Parameters in Patients with Obesity or Overweight and with or without Type 2 Diabetes: A Meta-Analysis of Randomized Controlled Trials

A ketogenic diet effectively promotes weight loss, glycemic control, and improved lipid profiles in overweight patients with type 2 diabetes mellitus.

Ketogenic Diet Benefits to Weight Loss, Glycemic Control, and Lipid Profiles in Overweight Patients with Type 2 Diabetes Mellitus: A Meta-Analysis of Randomized Controlled Trails

The ketogenic diet may improve microbiome diversity, epigenome, diabetes, weight loss, cardiovascular health, and cancer.

The Potential Health Benefits of the Ketogenic Diet: A Narrative Review

The ketogenic diet has potential benefits for obesity and type 2 diabetes, but current evidence is inconclusive and may not be sustainable.

The Ketogenic Diet for Obesity and Diabetes-Enthusiasm Outpaces Evidence.

Low-carbohydrate ketogenic diets effectively improve cardiovascular risk factors in obese/ overweight patients, especially those with type 2 diabetes mellitus, compared to non-ketogenic diets.

Low carbohydrate ketogenic diets reduce cardiovascular risk factor levels in obese or overweight patients with T2DM: A meta-analysis of randomized controlled trials

A ketogenic diet may have a positive impact on cardiovascular disease management, but more multidisciplinary studies are needed to confirm its true clinical benefit and justify its expanded clinical use.

Impact of ketogenic diet on cardiovascular disease.

A ketogenic diet shows no more benefits on nutritional parameters than a balanced diet, and sometimes has adverse effects.

Effect of a Ketogenic Diet on the Nutritional Parameters of Obese Patients: A Systematic Review and Meta-Analysis

The ketogenic diet shows promise for obesity and metabolic syndrome treatment, with no major side effects, but optimal carbohydrate proportion and diet duration need further exploration.

Beneficial Effects of the Ketogenic Diet in Metabolic Syndrome: A Systematic Review

A non-calorie-restricted ketogenic diet can optimize body mass and composition without compromising athletic performance in normal-weight individuals.

Ergogenic Properties of Ketogenic Diets in Normal-Weight Individuals: A Systematic Review

Ketogenic diets can improve glucose control and reduce medication use in type 2 diabetes patients, but require strict medical supervision and supportive psychological counseling for optimal results.

Efficacy of Ketogenic Diets on Type 2 Diabetes: a Systematic Review

Ketogenic diets show promise as a more effective and safe first-line approach for obesity and diabetes treatment, with potential benefits for cancer, neurodegenerative conditions, and other diseases associated with insulin resistance.

The Ketogenic Diet: Evidence for Optimism but High-Quality Research Needed

Ketogenic diets show potential in reducing seizure frequency in children with drug-resistant epilepsy, but more research is needed to confirm these findings.

Ketogenic diets for drug-resistant epilepsy.

Ketogenic diets are a safe approach for cancer patients reducing body weight and fat mass without significantly impacting cancer treatment-related indicators.

Effect of Ketogenic Diets on Body Composition and Metabolic Parameters of Cancer Patients: A Systematic Review and Meta-Analysis

The ketogenic diet improves glycemic and lipid control in patients with type 2 diabetes and significantly contributes to weight loss.

Effect of the ketogenic diet on glycemic control, insulin resistance, and lipid metabolism in patients with T2DM: a systematic review and meta-analysis

The ketogenic diet effectively improves glycemic control and lipid profile in diabetic patients, making it a recommended adjunctive treatment for type two diabetes.

Effects of the Ketogenic Diet on Glycemic Control in Diabetic Patients: Meta-Analysis of Clinical Trials

Ketogenic diets show significant weight loss in cancer patients, but no conclusive evidence for anti-tumor effects or improved overall survival.

The use of ketogenic diets in cancer patients: a systematic review

Ketogenic diets show limited improvements in obesity and type 2 diabetes, but may be associated with adverse events like nonalcoholic fatty liver disease and insulin resistance in rodents.

Effects of Ketogenic Diets on Cardiovascular Risk Factors: Evidence from Animal and Human Studies

The ketogenic diet may effectively induce weight loss and improve cardiovascular risk parameters in obese patients, but caution is needed due to potential side effects and potential risks.

Ketogenic Diet for Obesity: Friend or Foe?

A ketogenic diet has diverse health benefits, potentially benefiting neurological disorders, metabolic syndrome, and cancer, through metabolites acting as energy substrates, signaling molecules, and epigenetic modifiers.

Molecular Mechanisms Underlying the Bioactive Properties of a Ketogenic Diet

What are the latest findings on the benefits and risks of ketogenic diets?

Some studies suggest ketogenic diets improve weight loss, glycemic control, and lipid profiles, particularly in overweight or diabetic patients, while other studies highlight potential risks, lack of long-term safety data, and inconclusive evidence on sustainability and overall benefits.