Sleep deprivation is associated with various health risks, including cardiovascular, respiratory, neurological, gastrointestinal, immunology, dermatology, endocrine, and reproductive health.

Sleep deprivation and its association with diseases- a review.

Chronic sleep deprivation negatively impacts metabolic, cardiovascular, and nervous systems, with four potential biomarkers identified through proteomic analysis.

Proteomic analysis of rat serum revealed the effects of chronic sleep deprivation on metabolic, cardiovascular and nervous system

Sleep deprivation leads to decreased performance, alertness, and deterioration in health, increasing the risk of stroke, obesity, diabetes, cancer, cognitive deficits, osteoporosis, cardiovascular disease, and mortality.

What Is Sleep Deprivation?

Sleep deprivation impairs cognitive performance, leading to cognitive deficits in psychomotor and executive functions, working memory, and higher cognitive abilities, with genetic factors playing a role in vulnerability.

Neurocognitive Consequences of Sleep Deprivation

Chronic sleep deprivation is linked to an increased risk of depression in young women, but not in young men, with little evidence supporting effects on overall health status.

Chronic sleep deprivation and adolescent health: Two longitudinal studies of youth in Western Canada

Sleep deprivation, caused by lifestyle habits or sleep disorders, increases the risk of cardiovascular and metabolic diseases.

Sleep, sleep deprivation, autonomic nervous system and cardiovascular diseases

A high genetic risk for neuroticism doubles the cardiovascular risk associated with chronic sleep deprivation.

Abstract 16298: Higher Genetic Risk for Neuroticism Heightens Cardiovascular Risk Related to Chronic Sleep Deprivation

Short sleep duration is an independent risk factor for obesity and weight gain, potentially affecting appetite, physical activity, and thermoregulation.

Short Sleep Duration and Weight Gain: A Systematic Review

Chronic insomnia and shortened sleep are linked to increased risk of developing diabetes, hypertension, and cardiovascular disease.

The Effects of Insomnia and Sleep Loss on Cardiovascular Disease.

Sleep deprivation impairs endothelial function, potentially explaining the link between insufficient sleep and increased cardiovascular disease risk.

Effects of sleep deprivation on endothelial function in adult humans: a systematic review

Short-term sleep deprivation is associated with an increased risk of cardiovascular diseases, particularly in individuals aged 18 years and men.

The association between sleep deprivation and the risk of cardiovascular diseases: A systematic meta‑analysis

Chronic and acute-on-chronic sleep deprivation in residents negatively impacts cognitive performance, attention, executive functioning, and decision-making, potentially increasing the risk of medical errors.

Acute and chronic sleep deprivation in residents: Cognition and stress biomarkers

Sleep deprivation significantly impairs human functioning, with mood being more affected than cognitive or motor performance, and partial sleep deprivation having a more profound effect on functioning than long-term or short-term sleep deprivation.

Effects of sleep deprivation on performance: a meta-analysis.

Long-term interventions to reduce air pollution are expected to improve chronic sleep deficiency in urban communities.

Association of long-term exposure to air pollution with chronic sleep deprivation in adults from 141 urban communities in South Korea: a community-level longitudinal study, 2008‒2016

Sleep deprivation impairs memory and cognitive performance by altering gene expression and dendritic structure in neurons, affecting multiple levels of gene regulation.

Sleep and memory: The impact of sleep deprivation on transcription, translational control, and protein synthesis in the brain

Acute sleep deprivation increases the brain's response to hedonic food stimuli, potentially contributing to obesity in Western society.

Acute sleep deprivation enhances the brain's response to hedonic food stimuli: an fMRI study.

Chronic sleep disturbance, not sleep deprivation, is associated with self-reported health in adolescents, potentially impacting their wellbeing.

Chronic sleep disturbance, not chronic sleep deprivation, is associated with self-rated health in adolescents.

Poor sleep is linked to increased pain and inflammation in people with musculoskeletal conditions and chronic pain, highlighting the need for improved sleep interventions.

The Importance of Sleep for People With Chronic Pain: Current Insights and Evidence

Sleep deprivation leads to increased energy intake and unhealthy snacking, hindering weight loss efforts and affecting overall health.

Sleep Deprivation: Effects on Weight Loss and Weight Loss Maintenance

Short-term sleep deprivation significantly impacts cognitive performance across various domains, with time awake being a significant predictor of between-studies variability in accuracy measures.

A meta-analysis of the impact of short-term sleep deprivation on cognitive variables.

What are the latest findings on the health impacts of chronic sleep deprivation?

These studies suggest chronic sleep deprivation is associated with increased risks of cardiovascular, metabolic, neurological, and cognitive health issues, as well as conditions like obesity, diabetes, and depression.